Examples of 'variable heavy' in a sentence
Meaning of "variable heavy"
variable heavy - Refers to a situation where there are many variables that have a significant impact or importance
How to use "variable heavy" in a sentence
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variable heavy
Includes variable light and variable heavy framework regions.
The variable heavy and light chain components is preferably present on a single peptide chain.
Boundaries of the variable light and variable heavy domains are indicated by arrows.
The variable heavy chain can be peptide bonded to the carboxyl terminus of the toxin.
Framework regions include variable light and variable heavy framework regions.
Three humanised variable heavy chain variants were designed based on this framework.
The heavy chain variable region can be a humanized or human variable heavy chain variable region.
Isolation and selection of variable heavy chain and variable light chain coding pairs.
Variable heavy chain or variable light chain gene constructs are subcloned into appropriate expression vectors.
Fv fragments are heterodimers composed of a variable heavy chain and a variable light chain domain.
Antibodies and polypeptides can also comprise both a variable light chain and a variable heavy chain.
This is now the end of the variable heavy chain humanized amino acid sequence.
Figure 1b provides amino acid sequences of various antibody variable heavy regions.
Specific primers are used to amplify variable heavy and light chain domain nucleic acids.
The variable heavy chain region was cloned into an IgG 1 expression vector.
See also
Comparison of the variable heavy chain Fig.
The variable heavy chain sequence of the antibody is referred to in Tables 7 and 8.
In all experiments, the variable heavy chain was amplified.
An H-CDR3 region may be comprised within an antibody variable heavy chain.
The coding sequences for the variable heavy and light domains were determined by standard procedures.
A particularly useful masking molecule is derived from the variable heavy and light chain of McPc603.
The cDNA encoding the variable heavy and light chains was specifically amplified using PCR.
V heavy = V heavy sequence coding for a variable heavy chain of a GOI.
The complete variable heavy and light chain sequences are depicted in SEQ ID Nos.
V heavy = a sequence encoding a variable heavy chain of a GOI.
The variable heavy chain region of E11, wherein the constant region is from an IgG antibody.
VH and VI are antibody variable heavy and light chain respectively.
In certain embodiments, the purification tag is comprised in the variable heavy ( VH ) chain.
Antibodies, in part, comprise of a variable heavy chain and variable light chains.
The variable heavy chain region of E9, further comprising a signal peptide.
Example 9 describes the design of antibody variable heavy chain and kappa light chain leader primers.
The variable heavy chain region of E10 ; further comprising a constant region.
V Heavy = Sequence coding for the variable heavy chain of a GOI.
A variable heavy chain comprising the amino acid sequence shown in SEQ ID NO, 2 ;.
Typically, an antibody includes two variable heavy chain regions and two variable light chain regions.
Variable heavy ( VH ) consensus frameworks FIG.
In certain aspects, this is a variable heavy chain of a Fab that binds to a first epitope.
In some embodiments, the ESS11 is derived from the variable heavy chain ( VH ) gene.
The antibody may comprise a variable heavy region comprising the sequence of SEQ ID NO, 1.
Variable heavy ( VH ) chain regions of the CD47 antibodies are provided below.
Figure 52 shows the pJP h IgG1f variable heavy chain IgG expression vector.
Fig . 1A aligns variable heavy domain sequences and Fig . 1B aligns variable light domain sequences.
G1-VH shows the original murine variable heavy chain sequence.
IGHV1-69 human variable heavy chain germline acceptor amino acid sequence.
The fifth domain, D5, most closely resembles a variable heavy chain domain in length.
Fig.5A shows the variable heavy chain sequence of the initial antibody.
Figure 4 shows a sequence alignment of the variable heavy and light chain domain ( VH and VL ).
Cloning the variable heavy chain gene of the fibrin-specific antibody 59D8.
A number of human variable light ( VL ) and variable heavy ( VH ) consensus sequences have been identified.
The murine variable heavy region is amino acids I to 122.
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