Examples of 'voltage-gated sodium' in a sentence
Meaning of "voltage-gated sodium"
Voltage-gated sodium refers to a type of ion channel that controls the flow of sodium ions across the cell membrane in response to changes in electrical voltage. These sodium channels play a crucial role in the generation and propagation of action potentials in excitable cells, such as neurons and muscle cells. The opening and closing of voltage-gated sodium channels are tightly regulated and essential for proper cell communication and function
How to use "voltage-gated sodium" in a sentence
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voltage-gated sodium
Voltage-gated sodium channels are inactivated.
This wave causes a plurality of voltage-gated sodium channels to open.
The voltage-gated sodium channels are the classic targets of lidocaine.
Typical action potentials are initiated by voltage-gated sodium channels.
Voltage-gated sodium channels are believed to play a critical role in pain signaling.
It affects the gating of voltage-gated sodium channels and calcium channels.
Voltage-gated sodium channel blockers have clinical uses in addition to pain.
It has been shown to block the voltage-gated sodium channels at picomolar concentrations.
It does this through stabilization of the inactive state of voltage-gated sodium channels.
Thus, voltage-gated sodium channel blockers may be useful as anticonvulsant agents.
In certain embodiments, the second compound inhibits voltage-gated sodium channels.
Pyrethroids affect the voltage-gated sodium channels in vertebrates and non - vertebrates.
Compounds of the invention are useful as antagonists of voltage-gated sodium ion channels.
The brevetoxins bind to voltage-gated sodium channels, important structures of cell membranes.
In certain embodiments, the first compound inhibits voltage-gated sodium channels.
See also
Mutations in voltage-gated sodium channels are responsible for several monogenic epilepsy syndromes.
It is also important to stress the involvement of voltage-gated sodium channels in trigeminal neuralgia.
Voltage-gated sodium channels are transmembrane proteins which cause sodium permeability to increase.
The action potentials arise by the voltage-gated sodium and potassium channels.
Nonselective voltage-gated sodium channel blockade is responsible for LAs toxic properties.
Tetrodotoxin binds to what is known as site 1 of the fast voltage-gated sodium channel.
The blockade of voltage-gated sodium channels represents the primary action of those agents.
It remains unknown how exactly kalkitoxin binds to the voltage-gated sodium channel.
Lamotrigine blocks voltage-gated sodium channels and inhibits glutamate and aspartate release.
The mechanism of toxicity is through the blockage of fast voltage-gated sodium channels.
The voltage-gated sodium channels play a key role in the mechanism of neuronal excitability.
In order for excitability and conduction to occur, voltage-gated sodium channels must be activated.
Voltage-gated sodium channels are involved in the propagation of a nerve impulse across the neuron.
Bioactivity studies have shown that clathrodin changes the function of voltage-gated sodium channels.
Pyrethroids act as neurotoxics on voltage-gated sodium channels by slowing their activation and inactivation properties.
The object of the invention is to identify alternative compounds which modulate voltage-gated sodium channels.
The effect of bactridines on voltage-gated sodium channels has been observed under voltage clamp conditions.
Veratridine, a toxin that selectively promotes persistent activation of voltage-gated sodium channels, served as the stimulus.
Below this level, the voltage-gated sodium channels can not be opened by an activation signal.
Safinamide is associated with state-dependent inhibition of voltage-gated sodium Na.
Pyrethroids act as neurotoxins on voltage-gated sodium channels by slowing their activation and inactivation properties.
In individuals with HOPKK, a mutation impacts the voltage sensor or voltage-gated sodium channel.
Voltage-gated sodium channels have many different conformations, which can be classified into three states.
The sodium can not trigger the opening of the voltage-gated sodium channels as it becomes weaker.
Voltage-gated sodium channels are characterized as TTX sensitive or insensitive.
These studies suggested that lamotrigine acts presynaptically on voltage-gated sodium channels to decrease glutamate release.
Voltage-gated sodium channels Nav represent the classical targets of lidocaine.
Investigating anti-arrhythmic inhibition of voltage-gated sodium channels with unnatural amino acids and fluorescence spectroscopy.
Voltage-gated sodium channels are expressed in and mediate C-fiber nerve impulses.
Valproic acid also blocks the voltage-gated sodium channels and T-type calcium channels.
Voltage-gated sodium channel with group II receptor site domains highlighted in red.
Hainantoxins specifically inhibit tetrodotoxin-sensitive Voltage-gated sodium channels, thereby causing blockage of neuromuscular transmission and paralysis.
Voltage-gated sodium channels.
The abbreviation for the genes encoding for voltage-gated sodium channel starts with three letters, SCN.
Voltage-gated sodium channel.
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