Examples of 'antigen-binding domain' in a sentence
Meaning of "antigen-binding domain"
antigen-binding domain - a specific part of an antibody that binds to antigens, such as a virus or bacterium, to help the immune system identify and neutralize them
How to use "antigen-binding domain" in a sentence
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antigen-binding domain
Antibodies comprise at least one antigen-binding domain.
The spacer allows the antigen-binding domain to have a suitable orientation and reach.
It is however preferable that the minibodies comprise an antigen-binding domain.
A flexible spacer allows the antigen-binding domain to orient in different directions to facilitate binding.
The term also covers any polypeptide or protein comprising an antigen-binding domain of an antibody.
Both the antigen-binding domain and the ADP-ribosylation domain contain lysine residues.
The CAR-forming polypeptide provides the antigen-binding domain and hence the antigen specificity.
The antigen-binding domain may further comprise an antibody VI domain.
IgG and IgG-fragments without an antigen-binding domain may also be used as HLEPs.
An antigen-binding domain can also comprise only VH or only VI regions.
In one preferred aspect, the antigen-binding domain is formed from a Fv or a scFv.
Typicallly, such fragments would comprise an antigen-binding domain.
One example of an antigen-binding domain is an antigen binding domain formed by a VH-VL dimer.
The CAR may comprise an extracellular antigen-binding domain.
In another embodiment, the antigen-binding domain is a tumor antigen-binding domain.
See also
Typically, such fragments include an antigen-binding domain.
If the antigen-binding domain is a scFv, the co-stimulatory domain is fused to the scFv.
Typically, such fragments would comprise an antigen-binding domain.
A CAR typically has an extracellular antigen-binding domain linked to a transmembrane domain and endodomain.
Preferred antigen-binding molecules include, for example, substances having an antigen-binding domain of an antibody.
The antigen-binding domain of an antibody includes, for example, CDR and variable region.
Preferably, the co-stimulatory domain is placed at the N-terminus followed by the antigen-binding domain.
The antigen-binding domain may further comprise a human J k 5 gene.
The method of item 42, wherein the antigen-binding domain is a tumor antigen-binding domain.
The antigen-binding domain of the second CAR may bind to a membrane-distal epitope on CD22.
CDR3 and, particularly H3, are the greatest source of molecular diversity within the antigen-binding domain.
In some instances, the antigen-binding domain is a single chain Fv ( scFv ).
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Examples of using Domain
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All domain names must be in upper case
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Examples of using Antigen-binding
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The antigen-binding protein may be an antibody
Variable regions confer antigen-binding specificity
Antigen-binding proteins are not limited to antibodies
