Examples of 'ligand-binding domain' in a sentence
Meaning of "ligand-binding domain"
Ligand-binding domain: a specific region of a protein that binds to a signaling molecule (ligand) to initiate a biological response
How to use "ligand-binding domain" in a sentence
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ligand-binding domain
The same is true of the ligand-binding domain.
The ligand-binding domain is positioned on the extracellular side of the plasma membrane.
All of these molecules have an extracellular ligand-binding domain.
The extracellular ligand-binding domain can be specific for any antigen or epitope of interest.
The extracellular domain of a VEGF receptor is the ligand-binding domain.
More particularly, more than one ligand-binding domain is used in the expression construct.
The expression vector may further encode a second FKBP ligand-binding domain.
A soluble receptor includes the extracellular, ligand-binding domain of the corresponding cell surface receptor.
The ligand-binding domain may itself be a multi-domain structure.
The multi-spanning transmembrane protein comprises a ligand-binding domain which binds to an extracellular ligand.
The ligand-binding domain of the EGF-R, for example, resides in the extracellular domain.
A hybrid receptor will be created with a ligand-binding domain and DNA-binding domain from different sources.
The present invention provides antibodies that bind specifically to the ligand-binding domain of sFlt-1.
Each receptor contains a ligand-binding domain and a DNA-binding domain.
In another aspect, the immunomodulatory moiety includes an extracellular ligand-binding domain of TGF-BRII.
See also
The transmembrane region joins the ligand-binding domain to the Intracellular domain.
The class C GPCRs are distinguished by their large N-terminal tail, which also contains a ligand-binding domain.
In another aspect, the RM comprises a ligand-binding domain ( LBD ) or portion of such a domain.
The ecdysone receptor includes a transactivation domain, DNA-binding domain, and ligand-binding domain to initiate transcription.
In a particular embodiment, the ligand-binding domain is specific for CD19.
IFNAB-BPII is a soluble receptor, essentially corresponding to the extracellular, ligand-binding domain of IFNAB-BPI.
A chimeric nucleic acid sequence may encode a T1R ligand-binding domain within any 7-transmembrane polypeptide.
The RFP consists essentially of a transcription blocking domain, and a ligand-binding domain that regulates its activity.
In some embodiments, the ligand-binding domain.
Therefore, these antibodies appear to be directed against the ligand-binding domain of IL-18BPa.
In another embodiment, the RM comprises a ligand-binding domain ( LBD ).
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Examples of using Ligand-binding
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The receptor can be a ligand-binding fragment of a receptor
Dimerization or multimerization may provide increased ligand-binding affinity
Ligands and ligand-binding moieties are paired affinity tags