Examples of 'bispecific molecule' in a sentence
Meaning of "bispecific molecule"
bispecific molecule - a molecule that is designed to bind to two different targets or antigens simultaneously, commonly used in targeted therapy for diseases like cancer
How to use "bispecific molecule" in a sentence
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bispecific molecule
This is an important advantage of a bivalent bispecific molecule.
The bispecific molecule was injected over flow cells.
Again the heterodimerization of the desired bispecific molecule was very selective.
The bispecific molecule was designed as follows.
Activity was similar to that seen with freshly spiked bispecific molecule in serum.
The bispecific molecule can be designed to bind to any target of interest.
The tumor cell lysis achieved with diluted bispecific molecule was calculated accordingly.
A bispecific molecule of the invention can also be a single chain bispecific molecule.
In one embodiment, the bispecific molecule is a bispecific antibody.
The second / main peak represents the bispecific molecule.
An ideal bispecific molecule for human therapy should be undistinguishable from a normal IgG.
This may positively impact anti-tumor activity of the bispecific molecule.
A standard curve using fresh bispecific molecule was used to then calculate amount in serum.
This is illustrated in Figure 1 in the context of a bispecific molecule.
Quantity of bispecific molecule in serum was determined in the various samples using a qualified ELISA.
See also
The process of claim 27 further comprising recovering the bispecific molecule from the host cell culture.
The bispecific molecule was evaluated for its ability to activate T hybridoma cells in a stimulation assay.
In a specific embodiment, the bispecific molecule is a bispecific immunoadhesin.
The bispecific molecule of claim 18 further comprising an immunoglobulin sequence.
For dose-response assays, the bispecific molecule was serially diluted and added.
A bispecific molecule of claim 1, wherein the pathogen or pathogen component is a virus or viral component.
A composition comprising the bispecific molecule of claim 15.
For example, the bispecific molecule can bind to different binding sites of the same target.
In a standard assay, 5 µg of the bispecific molecule was finally added.
A bispecific molecule of Claim 3 wherein the anti-effector cell portion binds an Fca receptor.
A nucleotide sequence encoding the bispecific molecule of claim 15.
The bispecific molecule may comprise the first FN3 domain that binds EGFR comprising the sequence,.
A CD3 specific domain can be located Nor C-terminally in the bispecific molecule.
Alternatively, the bispecific molecule can bind to different target molecules.
The term " bispecific antibodies " is intended to include any anti-CD38 antibody, which is a bispecific molecule.
In a preferred embodiment, the bispecific molecule of the present invention is a bispecific antibody.
Bispecific molecule binding TLR9 and CD32 and comprising a T cell epitope for treatment of allergies.
The control B1Fab-sFb bispecific molecule does not induce T-cell proliferation.
The bispecific molecule of claim 8 ; and a pharmaceutically acceptable carrier.
The bispecific molecule of claim 8.
The bispecific molecule of claim 21 wherein said fusions are disulfide-linked.
A bispecific molecule comprising,.
A bispecific molecule comprising, an anti-effector cell portion and an anti-IgE portion.
The bispecific molecule of any one of claims 1-8, formulated together with a pharmaceutically acceptable carrier.
The term bispecific molecule also encompasses molecules which can recognize additional molecules ( i.e. are multispecific ).
A bispecific molecule of claim 1, wherein the virus component is the envelope glycoprotein gp41 of HIV.
A bispecific molecule of claim 1, which is.
A bispecific molecule comprising the immunobinder of any one of claims 1 to 15 or 17.
A bispecific molecule according to claim 1 or 2, wherein said bispecific molecule is a F ( ab ' ) 2 molecule.
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Examples of using Bispecific
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Bispecific antibodies have a higher cytotoxic potential
Methods for producing bispecific antibodies are known
Bispecific antibodies may be human or humanized antibodies
Examples of using Molecule
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A new molecule is found to prevent preterm birth
This part of the molecule right there
A molecule capable to desolating the black population
