Examples of 'bispecific single' in a sentence
Meaning of "bispecific single"
bispecific single - a term related to biochemistry or pharmaceuticals, often used in the context of describing a type of molecule or drug that can bind to two different targets or antigens simultaneously
How to use "bispecific single" in a sentence
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bispecific single
This molecular weight corresponds to the bispecific single chain antibody.
Bispecific single chain antibodies can be encoded by a single nucleic acid molecule.
Expression and purification of the CEAxCD3 bispecific single chain antibodies.
Bispecific single chain antibodies with specificity for high molecular weight target antigens.
In one embodiment, the bispecific antibody is a bispecific single chain antibody.
The bispecific single chain antibody could be specifically detected by Western Blot.
A pharmaceutical composition comprising the bispecific single chain antibody of claim 1.
However, bispecific single chain antibodies must fulfil additional requirements.
Flow cytometric binding analysis of the CEAxCD3 bispecific single chain antibodies.
Additional examples of bispecific single chain antibodies can be found in PCT application No.
Maximal cytokine release was observed after administration of 10 µg of bispecific single chain antibody.
Resistance of human CEAxCD3 bispecific single chain antibodies to soluble CEA antigen.
Maximal cytokine release was observed after administration of 10 microgram of bispecific single chain antibody.
The bispecific single chain antibodies were expressed in chinese hamster ovary ( CHO ) cells.
A single band was detected at 52 kD corresponding to the purified bispecific single chain antibody molecule.
See also
Formats of bispecific single chain antibody molecules comprising anti-CEA and anti-CD3 specificities ( Table 1 ).
Said CD3 binding domain is contained in or is comprised by a bispecific single chain antibody.
An advantageous variant of this bispecific single chain antibody is from N terminus to C terminus,.
EXAMPLE 8, Generation and cytotoxic activity of human CEAxCD3 bispecific single chain antibodies.
Construction of CD19xCD3 and CD3xCD19 bispecific single chain antibodies comprising various domain rearrangements.
Figure 36, FACS binding analysis of cross-species specific bispecific single chain construct SEQ ID NO.
Construction of tetravalent bispecific single chain antibodies is taught in Coloma and Morrison, 1997, Nat.
EXAMPLE 4, Bioactivity of CEAxCD3 bispecific single chain antibodies.
EXAMPLE 2, Generation of CEAxCD3 bispecific single chain antibodies.
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Examples of using Bispecific
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Bispecific antibodies have a higher cytotoxic potential
Methods for producing bispecific antibodies are known
Bispecific antibodies may be human or humanized antibodies
