Examples of 'chain variable' in a sentence
Meaning of "chain variable"
chain variable: In programming or statistics, a chain variable is a variable that is dependent on other variables in a sequence or chain. Changes in one variable can affect the subsequent variables in the chain.
How to use "chain variable" in a sentence
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chain variable
E light chain variable domain nucleotide sequence.
Various aspects encompass light chain variable domains.
E heavy chain variable domain nucleotide sequence.
Various embodiments encompass light chain variable domains.
Single chain variable regions may be produced either recombinantly or synthetically.
Isolation of rearranged kappa light chain variable segments.
A suitable light chain variable framework region was designed in a similar manner.
Exemplary peptide chains being compared are heavy or light chain variable regions.
A suitable light chain variable framework region can be designed in a similar manner.
Such residues are typically derived from a heavy chain variable domain.
Light chain and heavy chain variable regions were amplified in separate reactions.
The other sequence was typical of a functional mouse kappa chain variable region.
The cloned cDNAs encoding the light chain variable regions were analyzed by sequencing.
No donor framework residues were retained in the engineered light chain variable region.
The amplified heavy and light chain variable regions were sequenced.
See also
The light chain variable region can be a humanized or human light chain variable region.
Regions outside heavy and light chain variable regions are underlined.
In the heavy chain variable domain there is an unusual feature in the framework region.
A preferred imaging marker gene is a single chain variable fragment from an antibody.
Any of the light chain variable regions may be combined with a suitable constant region.
Analyze the heavy chain and light chain variable region sequences.
Any of the heavy chain variable regions may be combined with a suitable human constant region.
A heavy chain refers to any polypeptide that a heavy chain variable domain.
The cDNAs encoding heavy and light chain variable domains are isolated from a hybridoma.
Typically the chimeric antibody comprises both light and heavy chain variable domains.
The heavy and light chain variable region sequences are shown in the sequence listing.
The multivalent antibody herein four light chain variable domain polypeptides.
The light chain variable domain is aligned with the variable domain of the heavy chain.
The antibody contains a mature heavy chain or light chain variable region sequence.
The light chain variable region is separated from heavy chain variable region by a linker region.
The nucleic and amino acid sequences of these light chain variable regions are.
The heavy chain variable region can be a humanized or human variable heavy chain variable region.
This is done independently for both the heavy and light chain variable domain sequences.
The light chain variable region is aligned with the variable region of the heavy chain.
This is done independently for both the heavy and light chain variable region sequences.
A heavy chain variable region and the constant region of another subclass can be directly linked.
Typically the chimaecic antibody comprises both light and heavy chain variable domains.
The heavy chain variable regions of such antibodies can be derived from any selected antibodies.
Typically the chimaeric antibody comprises both light and heavy chain variable domains.
Chimeric heavy chain variable region and signal nucleotide and amino acid sequences are provided.
The present invention also provides antibodies comprising such light chain variable regions.
Method of cloning a lambda light chain variable domain using a human lambda light chain mouse.
A common denominator of such specific binding bodies is the presence of a heavy chain variable domain.
The binding domain polypeptide can be a heavy chain variable region or a light chain variable region.
The above first and second polypeptides may additionally comprise an antibody heavy chain variable region.
Harvesting the immunoglobulin heavy chain variable region and the immunoglobulin light chain variable region.
Polynucleotide and polypeptide sequences of particular light and heavy chain variable domains are shown below.
A humanized heavy chain variable region is illustrated in Fig.
Typically the antigen binding region comprises both light and heavy chain variable domains.
VHH denotes heavy chain variable domain of a heavy chain immunoglobulin.
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