Examples of 'deacetylase activity' in a sentence
Meaning of "deacetylase activity"
Deacetylase activity: Refers to the enzymatic activity that catalyzes the removal of acetyl groups from a substrate, often involved in various biological processes
How to use "deacetylase activity" in a sentence
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deacetylase activity
It possesses histone deacetylase activity and represses transcription when tethered to a promoter.
The invention further provides methods of modulating tubulin deacetylase activity in a cell.
The supernatant extract having deacetylase activity was aliquotted and frozen for storage.
The deletion construct is then expressed and assayed for chitin deacetylase activity.
Histone deacetylase activity from crude nuclear extract derived from HeLa cells was used for screening.
Class IIa HDAC can repress transcription independent of the deacetylase activity.
Nor Frye test sirtuin deacetylase activity on a cellular polypeptide.
Figure 5 is a diagram which represents the pH dependence of chitin deacetylase activity.
A negative control without histone deacetylase activity and a positive control without HDAC inhibitor are treated likewise.
HDAC activity corresponds to the level of histone deacetylase activity of the HDAC.
In some embodiments, deacetylase activity is increased by increasing the activity of HDAC8.
Figure 4 is a diagram which represents the temperature dependence of chitin deacetylase activity.
In some embodiments, increased deacetylase activity is protective in neuronal cells.
We then demonstrated that HDAC3 acts independently of its deacetylase activity.
The compound increases deacetylase activity of the sirtuin protein ;.
See also
Example 15 In vitro measurement of the inhibitory capacity of histone deacetylase activity.
Graph showing that genetically reducing deacetylase activity in Sin3A heterozygotes slows degeneration.
Also described herein is a pharmaceutical composition for increasing a level or deacetylase activity of SIRT3.
Thereby a candidate agent increasing deacetylase activity of a SIRT3 polypeptide is identified.
In some embodiments, the activity increase of HDAC is an increase in HDAC deacetylase activity.
The temperature dependence of the chitin deacetylase activity is shown graphically in Figure 1.
This experiment indicates that VPA or a metabolite formed in F9 cells inhibits histone deacetylase activity.
In some embodiments, deacetylase activity is increased by adding an HDAC activator to the cell.
When the fungus grows through the stomatal opening, chitin deacetylase activity increases drastically.
In some embodiments, deacetylase activity is increased by increasing the activity of class I HDAC.
S1P has been shown to directly inhibit the histone deacetylase activity of HDACs.
Detecting SIRT3 Deacetylase Activity Various assays have been described to detect sirtuin deacetylase activity.
EZH2-mediated cell invasión required an intact SET domain and histone deacetylase activity.
A preferred activity of SIRT3 is the deacetylase activity of SIRT3, preferably the deacetylation of AceCS2.
Mammalian Sir2 homologs have NAD-dependent histone deacetylase activity.
The lack of histone deacetylase activity allowed the acetylation of H3K9 and histone H4.
Mammalian Sir2 homo logs have NAD-dependent histone deacetylase activity.
All class II HDACs showed abundant deacetylase activity on the acetylated H4 peptide ( figure 3D ).
SIRT1 is the human homolog of the yeast Sir2 protein and exhibits NAD-dependent deacetylase activity.
Polypeptides according to the invention having hydrolytic and / or deacetylase activity includes Glyco hydro 114 glycosyl hydrolases.
Deacetylase activity in the presence or absence of 200 □ M NAD was measured.
However, none of the class II HDACs tested contained tubulin deacetylase activity ( figure 3D ).
A further increase in NAD concentration to 10 mM resulted in a reduction in deacetylase activity ( Figure 1A ).
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Examples of using Deacetylase
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Squaric acid derivatives as inhibitors of histone deacetylase
Inhibition of histone deacetylase as a treatment for cardiac hypertrophy
Compounds for the inhibition of histone deacetylase
Examples of using Activity
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There is a lot of activity happening in that room
Activity cards divided into four themes
Refrain from physical activity until symptoms are gone
