Examples of 'deacetylases' in a sentence
Meaning of "deacetylases"
Deacetylases are enzymes that catalyze the removal of acetyl groups from proteins, often involved in regulating gene expression and other cellular processes
Show more definitions
- plural of deacetylase
How to use "deacetylases" in a sentence
Basic
Advanced
deacetylases
Characterization of class IIb mammalian histone deacetylases.
Histone deacetylases have been grouped into three classes.
The sirtuins are a class of histone deacetylases that inhibit gene expression.
Gene expression might be influenced by the enzymes histone acetyltransferases HATs and histone deacetylases HDACs.
Histone deacetylases in the nucleolus.
Some derivatives of hydroxamic acid which inhibit histone deacetylases are known.
A number of yeast histone deacetylases and plant histone deacetylases have also been identified.
Long range interactions at the GAL locus are influenced by lysine deacetylases.
Histone acetylases and deacetylases play a major role in the control of gene expression.
TPX and TSA have emerged as potent inhibitors of histone deacetylases.
Disruption of the neurogenic program implying histone deacetylases was shown to alter cell differentiation.
It blocks one of the key enzymes involved in epigenetic changes, histone deacetylases.
Largazole specifically targets histone deacetylases whose dysfunction is often associated with a variety of human tumors.
Accordingly, improved assays for measuring the activity of acetyltransferases or deacetylases are needed.
We present evidence that histone deacetylases exert a negative effect on Pol III activity in vivo.
See also
Recently, certain compounds that induce differentiation have been reported to inhibit histone deacetylases.
Other preferred histone deacetylases include class III enzymes.
Therefore the correct name for HDACs would be lysine-specific protein deacetylases.
Several cephalosporin C deacetylases are provided herein having significant perhydrolysis activity.
The yeast Sir2 protein belongs to a family of histone deacetylases.
Preferred histone deacetylases include class I and class II enzymes.
HDACIs, in particular, are known to interfere with or tend to interfere with histone deacetylases.
They have anti-inflammatory and histone deacetylases inhibition properties.
Histone deacetylases ( HDACs ) are a class of enzymes that remove acetyl groups from histones.
Sirtuins are a conserved family of NAD+ - dependent deacetylases that are involved in various processes.
Histone deacetylases ( HDACs ) are a group of enzymes responsible for deacetylation of histones and nonhistone proteins.
In some embodiments, neurological disorders are treated by increasing the activity of class I histone deacetylases.
Histone deacetylases can be regulated by endogenous factors, dietary components, synthetic inhibitors and bacteria-derived signals.
In addition, NCOR2 appears to recruit histone deacetylases to DNA promoter regions.
Histone deacetylases ( HDAC ) catalyze the removal of acetyl groups from histones.
The antisense transcripts are associated with the Hda1 lysine deacetylases Fig.
The third class of deacetylases consists of the members of the Sir2 family of enzymes.
Sirtuins are Class III NAD-dependent histone deacetylases.
More specifically, histone deacetylases remove an acetyl group from an N-acetyl lysine on a histone.
Features, A specific inhibitor of class IIB histone deacetylases.
Class I and class II histone deacetylases ( HDACs ) are zinc containing hydrolase enzymes.
Histone acetylation and deacetylation is catalysed by histone acetyltransferases ( HATs ) and histone deacetylases ( HDACs ).
As described herein, several cephalosporin C deacetylases are provided having significant perhydrolysis activity.
A SIRT1 protein refers to a member of the sir2 family of sirtuin deacetylases.
In contrast, histone deacetylases ( HDACs ) are part of transcriptional corepressor complexes.
Yeast Sir2 and some, but not all, sirtuins are protein deacetylases.
There are a number of histone deacetylases in yeast, including the following,.
Furthermore, bufexamac was identified as a specific inhibitor of class IIB histone deacetylases HDAC6 and HDAC10.
It restores histone deacetylases ( HDAC ), thereby restoring corticosteroid function.
Class III are the NAD+ - dependent protein deacetylases.
HATs are responsible for acetylation ; whereas histone deacetylases ( HDACs ) are responsible for histone deacetylation.
Abstract, Histone deacetylases ( HDACs ) are the major targets of currently FDA-approved anti-cancer epigenetic drugs.
Subsequently, two other nuclear mammalian deacetylases were found, HDAC2 and HDAC3.
Histone Deacetylases ( HDACs ) and Cancer.
Espically class1 Histone deacetylases ( HDAC ) family of molecules.
