Examples of 'dose-limiting' in a sentence
Meaning of "dose-limiting"
Dose-limiting refers to a treatment effect or side effect that prevents increasing the dosage of a medication
How to use "dose-limiting" in a sentence
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dose-limiting
No dose-limiting toxicity was seen in clinical trials.
Neurotoxicity is the dose-limiting toxicity of nelarabine.
Renal toxicity is not usually dose-limiting.
And no dose-limiting toxicities have been observed.
Myelosuppression is usually the dose-limiting toxicity.
No dose-limiting toxicity was observed during clinical trials.
Thrombocytopenia has been the dose-limiting toxicity.
The dose-limiting adverse reaction was postural hypotension.
Myelosuppression is most often dose-limiting.
Myelosuppression is a dose-limiting undesirable effect of mitoxantrone.
Cardiovascular toxicity is usually dose-limiting.
No dose-limiting toxicities were observed during clinical studies.
No subject experienced a dose-limiting toxicity.
The dose-limiting toxicity was neutropenia.
Such side effects are frequently dose-limiting in a subject.
See also
The dose-limiting toxicity of this agent is myelosuppression.
Gastrointestinal toxicity was dose-limiting in a single ascending dose study.
The dose-limiting parasite had not been specified or selected.
Gastrointestinal toxicity is the dose-limiting side effect of tegafur.
No dose-limiting toxicities have been observed during clinical trials.
This route has drawbacks such as dose-limiting phlebitis.
However, a fundamental dose-limiting factor of cisplatin treatment is nephrotoxicity.
The combination of temsirolimus and sunitinib resulted in dose-limiting toxicity.
Myelosuppression is the dose-limiting toxicity of carboplatin injection.
Dose-limiting toxicity with the current schedules was diarrhea.
Bone marrow depression is the dose-limiting toxic effect of hydroxycarbamide.
The dose-limiting toxicities of lenalidomide were neutropenia and thrombocytopenia.
Excellent tolerability continued to be observed, with no dose-limiting safety signals.
No dose-limiting toxicities have been observed during clinical trials of etanercept.
All of these drugs may have dose-limiting side effects.
A dose-limiting sleeve is coupled to at least one of the two structures.
Treatment may have to be modified if dose-limiting host toxicity develops.
No dose-limiting toxicities were observed during clinical trials of rheumatoid arthritis patients.
The main outcome measures were adverse reactions and dose-limiting toxicities.
No dose-limiting toxicities were observed during clinical trials in rheumatoid arthritis patients.
Nausea and vomiting can be distressing and in some cases dose-limiting.
If no dose-limiting toxicities are observed, three patients are treated on the next schedule.
Gastrointestinal damage is the primary dose-limiting toxicity of a mixture of tegafur and uracil.
Dose-limiting toxicity with these compounds is usually urinary tract toxicity.
However, one of their main and frequently dose-limiting side effects is hyperglycaemia.
The usual dose-limiting toxicity for an alkylating agent is hematopoietic toxicity.
No drug-related serious adverse events occurred and no dose-limiting toxicity was observed.
However, it too has dose-limiting side effects such as nephrotoxicity and ototoxicity.
Diarrhoea can have an early or late onset and can be a dose-limiting factor.
Gastrointestinal toxicity was dose-limiting in rats and monkeys, as the intestine was a consistent target organ.
An example is in the accelerated fractionation regime, in which acute reactions can be dose-limiting.
In the toxicological studies with etanercept, no dose-limiting or target organ toxicity was evident.
Due to dose-limiting toxicity, clinical therapeutic exposure levels could not be reached in animals.
This allows a detailed investigation of extramedullary dose-limiting toxicity of the parenteral formulation.
Mitotic inhibitors can damage the peripheral nervous system, and hence are dose-limiting.
