Examples of 'fc portion' in a sentence
Meaning of "fc portion"
FC portion: This could refer to various contexts such as Football Club portion, Financial Contribution portion, etc. More context is needed to provide an accurate definition
How to use "fc portion" in a sentence
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fc portion
This is due to the Fc portion of the antibody.
The Fc portion of an antibody is oxidized to form an aldehyde.
Regions corresponding to the Fc portion are shown in bold.
An Fc portion may be selected so as to be appropriate to the organism.
Various substitutions or mutations to the Fc portion of an antibody are described herein.
The Fc portion of the immunoglobulin chain may be proinflammatory in vivo.
It may comprise an Fc portion of an antibody.
The Fc portion can further include one or more glycosylation sites.
A hemidimeric antibody is made up of an Fc portion and one Fab portion.
The Fc portion of the immunoglobulin mediates certain effector functions of an immunoglobulin.
The carrier molecule may be an immunoglobulin or the Fc portion of an immunoglobulin.
Z is an Fc portion of an antibody molecule.
The heavy chain polypeptide can comprise an Fc portion of an immunoglobulin molecule.
These same cysteines permit efficient and consistent disulfide bonding formation of an Fc portion.
Antibodies need an Fc portion to exert cytotoxic activity.
See also
Etanercept is a dimeric fusión protein consisting of the Fc portion of human IgG.
The Fc portion is also referred to herein as the Fc region.
It does not have an Fc portion.
The Fc portion may bind to one or more Fc receptors or Fc ligands.
The hinge connects the Fab region to the Fc portion of the IgG molecule.
The method comprises administration of a chimeric polypeptide comprising a FVIII portion and an Fc portion.
Fc Portion The antibody variable domains are optionally fused to an Fc portion.
ADCC involves cell lysis by effector cells that recognize the Fc portion of an antibody.
The Fc portion of the fusión protein is bound by the Protein G on the column.
The second amino acid sequence may be derived from the Fc portion of an IgG.
For example, the Fc portion can be biotinylated.
Polyclonal and some monoclonal antibodies contain carbohydrates in the Fc portion of the antibody.
The Fc portion of an antibody mediates several important effector functions e . g.
The methods comprise administration of a chimeric polypeptide comprising a FVIII portion and an Fc portion.
This is the result of glycosylation of the Fc portion and the C terminal extension.
The Fc portion comprises the amino acid sequence of a native human Fc region ;.
A protein A sepharose column was used to capture the Fc portion of the fusión proteins.
Substitutions in the IgG4 Fc portion of the fusión protein are indicated in parenthesis.
In other embodiments, the antibody lacks an Fc portion.
More preferably, the human Fc portion is derived from an IgG antibody.
In another preferred embodiment, the fusión protein comprises an Fc portion of an immunoglobulin.
The Fc portion may derive from human antibodies or non-human antibodies.
In one embodiment, the Fc portion is human.
The Fc portion of the immunoglobulin is responsible, in part, for this in vivo stability.
In the present invention, the Fc portion typically includes at least a CH2 domain.
The Fc portion extends the circulatory half-life of the constructs in vivo.
Preferably, the antibody according to the present invention comprises an Fc portion of an IgG.
These cells express receptors for the Fc portion of immunoglobulins or complement receptors, or both.
The peptide according to claim 6, characterized in that the ligand is an immunoglobulin Fc portion.
An antibody according to Claim 7, wherein said Fc portion has reduced effector function.
In addition to binding units, biMabs also include linker polypeptides and an Fc portion.
A schematic of the Fc portion of a clone is shown in Figure 4.
An antibody according to any preceding claim, wherein said antibody has an Fc portion.
Examples of opsonins are the Fc portion of an antibody or compliment C3.
Fc receptors ( FcR ) are leukocyte surface glycoproteins that specifically bind the Fc portion of antibodies.
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