Examples of 'heavy and light chains' in a sentence
Meaning of "heavy and light chains"
In immunology, heavy and light chains refer to the two types of polypeptide chains that make up an antibody. Heavy chains are larger and provide structural support, while light chains are smaller and help with antigen recognition.
How to use "heavy and light chains" in a sentence
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heavy and light chains
Antibodies are composed of heavy and light chains.
Both heavy and light chains are folded into domains.
Preferred antibodies include both heavy and light chains.
The humanised heavy and light chains were constructed as follows.
The antibodies comprise humanized heavy and light chains.
Antibody heavy and light chains are cloned in a mammalian vector system.
The arrows indicate the FabM heavy and light chains.
Constant heavy and light chains that are from a human antibody.
Mercaptoethanol reduction of an antibody yields individual heavy and light chains.
Different types of heavy and light chains are recognized.
Underlined sequences represent CDRs of the heavy and light chains.
The heavy and light chains are joined together by disulfide bonds.
These are the hypervariable regions of immunoglobulin heavy and light chains.
The immunoglobulin heavy and light chains are connected by an interchain disulfide bond.
Reverse primers are located in the constant regions of heavy and light chains.
See also
Heavy and light chains are indeed composed of constant and variable domains.
This may be used for expressing heavy and light chains of an antibody.
Naturally occurring antibodies are immunoglobulin molecules consisting of heavy and light chains.
Expressing the heavy and light chains from the fusión polynucleotides.
These antibodies may include two identical heavy and light chains.
The antibodies are made up of heavy and light chains linked together by disulphide bonds.
The following procedure is utilized for both heavy and light chains.
Pronounced antibody heavy and light chains could be observed in the same amounts.
A classic example of heterodimerization is provided by the heavy and light chains of an antibody.
Both heavy and light chains comprise a variable domain and a constant part.
The primary sequences of the heavy and light chains are known in the art.
They are located in the variable regions of the antibody heavy and light chains.
Each of the heavy and light chains also has an intrachain disulfide bond.
The polynucleotide is expressed to produce the heavy and light chains in the patient.
The recombinant heavy and light chains are also marked using a systematic nomenclature.
These regions are located in the variable regions of the antibody heavy and light chains.
The complete nucleotide sequence of the heavy and light chains were confirmed by sequencing.
The heavy and light chains each comprise a variable region and a constant region.
Only the variable regions of the heavy and light chains need to be cloned.
Heavy and light chains each contain intrachain disulfide bonds which stabilize their folding.
The variable domains of the heavy and light chains function together in antigen binding.
The deconvoluted mass spectrum represents the masses of the heavy and light chains.
The order of the heavy and light chains is not limiting and can be reversed.
Multiple plasmid clones were sequenced for each of the heavy and light chains variable regions.
The molecule consists of heavy and light chains held together covalently through disulfide bonds.
Disclosed here are methods for preparing extremely diverse libraries of antibody heavy and light chains.
The strategy for cloning heavy and light chains as separate elements is depicted in fig.
Positive clones may be screened using appropriate probes for the heavy and light chains required.
The variable domains of the heavy and light chains have the same general structure.
The resulting reduced sections from the globulin molecule are free intact heavy and light chains.
One or more variable regions of the first heavy and light chains comprise humanized sequences.
The heavy and light chains are both divided into variable domains and constant domains.
Each resulting plasmid has both the heavy and light chains encoded in one vector.
The heavy and light chains selected may be from the same or different human antibodies.
Multiple methods are provided for coupling the heavy and light chains from single cells.
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