Examples of 'light and heavy chain' in a sentence
Meaning of "light and heavy chain"
light and heavy chain - two types of chains which differ in weight or the materials they are made of
How to use "light and heavy chain" in a sentence
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light and heavy chain
Construction of humanized light and heavy chain genes.
Reduced light and heavy chain analysis also shown.
We present the sequences of light and heavy chain CDRs below.
Both the light and heavy chain vectors also integrated.
Preferably the antibody comprises a light and heavy chain of an antibody.
Human light and heavy chain ferritin cDNA having defective iron regulatory elements were used.
Typically the chimeric antibody comprises both light and heavy chain variable domains.
The most similar light and heavy chain amino acid sequences were retrieved.
This is achieved by selecting primers amplifying only one isotype of light and heavy chain.
The variable light and heavy chain regions are preferably present as a single amino acid sequence.
Typically the chimaecic antibody comprises both light and heavy chain variable domains.
Both the light and heavy chain residues were completely sequenced using the dideoxynucleotide method.
Typically the chimaeric antibody comprises both light and heavy chain variable domains.
The CDRs of the light and heavy chain are marked on these Figures.
Typically the antigen binding region comprises both light and heavy chain variable domains.
See also
The Fab light and heavy chain genes were transcribed as a single dicistronic message.
Polynucleotide and polypeptide sequences of particular light and heavy chain variable domains are shown below.
For both the light and heavy chain transformations, 2 microliters of ligation reactions were used.
Five and six independent sequences are used to assemble the light and heavy chain sequences.
Single chain antibodies comprise the light and heavy chain variable regions linked by a flexible linker.
The light and heavy chain variable regions can, optionally, be ligated to corresponding constant regions.
The chosen human antibody will then provide both light and heavy chain acceptor sequences.
Sequences of the light and heavy chain variable regions were determined in the following manner,.
Verification of product Detection of light and heavy chain assemblies.
FIG . 9 shows the light and heavy chain CDRs as determined by the Kabat definitions.
A standard PCR reaction of the phage amplified the light and heavy chain of the Fab.
By genetic engineering, from light and heavy chain immunoglobulin genes belonging to different species.
The antigen-binding fragment may also comprise a portion of an immunoglobulin light and heavy chain.
An example of a vector containing such light and heavy chain sequences is depicted in FIG . 1.
Reduced light and heavy chain analysis also shown, with respective average CA per chain.
Typically, the chimaeric antibody comprises both light and heavy chain variable regions.
Both the light and heavy chain reactions contained 2 microliters of the appropriate purified PCR product.
Similarly, the consensus sequences for human light and heavy chain subgroups also available.
The light and heavy chain vectors are described in Tables 2 and 3, respectively.
Several vectors containing cDNAs encoding light and heavy chain sequences of H11 were prepared.
The light and heavy chain expressing plasmids were then co-transfected into Cos-7 cells.
Example 5, Evaluation method for Ame55 light and heavy chain variable region mutant Alanine scanning.
The light and heavy chain V region sequences of HuGAL-FR21 are shown in Fig.
In embodiment, the fragment comprises the light and heavy chain hypervariable regions of mAb 1479.
The light and heavy chain of Fab-H were produced in equal amounts ( Figure 9 ).
Finally, plasmid p4821 for expression of both antibody light and heavy chain was transfected alone.
Cloning of light and heavy chain variable regions of anti-CD162 antibodies.
There is one beneficial mutation in both light and heavy chain CDR3 in clone 111.
Cloning the variable light and heavy chain genes of the fibrin-specific antibody 64C5.
Examples 11 and 12 provide variants in light and heavy chain CDR3 region of AT antibody.
Chromatogram 1 ; ABX ™ pool containing light and heavy chain contaminants present before LPHIC purification.
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