Examples of 'hypervariable regions' in a sentence
Meaning of "hypervariable regions"
hypervariable regions: In genetics, these are specific areas in DNA sequences that exhibit high levels of genetic variation among individuals
How to use "hypervariable regions" in a sentence
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hypervariable regions
Hinge regions are the hypervariable regions of a flagellin.
The hypervariable regions are underlined and in bold.
Consists of one of the hypervariable regions or loops.
The hypervariable regions can be cloned and sequenced.
Alternatively some genes may contain hypervariable regions.
The extended hypervariable regions are boxed.
There can be substitutions in both these hypervariable regions.
Hypervariable regions are usually called.
The CDRs are commonly referred to as the hypervariable regions.
It was conjectured that the hypervariable regions are involved in antigen binding.
Hypervariable regions that were not replaced during the mutagenesis are shown in bold.
The residues from each of these hypervariable regions are noted below.
These hypervariable regions are also called complementarity determining regions or CDRs.
One or more of these positions can also be found in extended hypervariable regions.
These are the hypervariable regions of immunoglobulin heavy and light chains.
See also
The invention also relates to fusión polypeptides comprising these variant hypervariable regions.
Computer analysis indicates that all three hypervariable regions are hydrophilic and antigenic.
The hypervariable regions as defined by Kabat et al.
Antibody CDRs may be identified as the hypervariable regions originally defined by Kabat et al.
CDRs or hypervariable regions may for example be identified by sequence alignment to other antibodies.
The FR of the variable domain generally show less sequence variability than the hypervariable regions.
This finding indicated that the two hypervariable regions under investigation may be in close contact.
Preferably, there are substitutions in both these hypervariable regions.
CDRs are the hypervariable regions of immunoglobulin heavy and light chains.
The regions QQA and LWTTRAGNP are hypervariable regions.
There are two mitochondrial hypervariable regions used in human mitochondrial genealogical DNA testing.
The altered antibodies will have mutation ( s ) in one or more hypervariable regions thereof.
The amino acid sequences of the hypervariable regions and the DNA sequences coding for them.
Hypervariable regions as antigenic determinants in the ORF 5 envelope protein.
The rest of the V region between the hypervariable regions are called framework regions.
The “ contact ” hypervariable regions are based on an analysis of the available complex crystal structures.
Antibodies are remarkably specific, thanks to hypervariable regions in both light and heavy chains.
In contrast, certain portions of a V region are highly variable and are designated hypervariable regions.
The DR set may contain three hypervariable regions of a heavy or light chain V region.
Hypervariable regions from the murine antibodies were engineered into VLK2 and VHL acceptor frameworks.
These areas have been termed hypervariable regions or complementarity determining regions ( CDRs ).
Site-directed mutagenesis was also conducted to examine the hypervariable regions more closely.
As a whole, the six hypervariable regions confer antigen-antibody specificity to the antibody.
The antigen-binding site is formed by the hypervariable regions of a VH, VI pair.
It includes hypervariable regions ( COMPLEMENTARITY DETERMINING REGIONS ) and framework regions.
The shaded portions marked v1 to v5 indicate hypervariable regions.
In most cases these hypervariable regions correspond to, but may extend beyond, the CDRs.
Amino acid mutations in one or more hypervariable regions ( HVRs ) e . g.
In most cases these hypervariable regions correspond to, but may extend beyond, the CDR.
These mutations occur mostly at " hotspots " in the DNA, which are concentrated in hypervariable regions.
Accordingly, the regions other than such hypervariable regions may be derived from other antibody.
These hypervariable regions are usually referred to as Complementarity Determining Regions ( CDR ).
Table 4, Amino acid sequences of the hypervariable regions of the secukinumab monoclonal antibodies.
Such hypervariable regions are also referred to as " complementarity determining regions " or " " regions.
The residues from each of these hypervariable regions are noted below . Loop Kabat.
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Examples of using Hypervariable
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Hinge regions are the hypervariable regions of a flagellin
The hypervariable regions are underlined and in bold
Consists of one of the hypervariable regions or loops
Examples of using Regions
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Regions number of countries with evaluation plans
Some countries or regions have multiple patterns
Regions are hit differently by restructuring of the economy
