Examples of 'immunoglobulin fc' in a sentence
Meaning of "immunoglobulin fc"
immunoglobulin fc - Immunoglobulin Fc (Fragment crystallizable) is a part of an antibody molecule that plays a crucial role in the immune response. It is responsible for binding to immune cells and triggering various immune functions, such as phagocytosis and inflammation, upon recognizing pathogens or foreign substances
How to use "immunoglobulin fc" in a sentence
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immunoglobulin fc
A pharmaceutical composition comprosing an immunoglobulin fc as a carrier.
Preferred is an immunoglobulin Fc domain which can be used as a carrier.
Within one embodiment the affinity tag is an immunoglobulin Fc polypeptide.
An immunoglobulin Fc region overexpressed as inclusion bodies may be purified through a general technique.
A method for the mass production of immunoglobulin fc region deleted initial methionine residues.
The second polypeptide fusión partner comprises an immunoglobulin Fc domain.
Preferred is a recombinant immunoglobulin Fc domain derived from the human Fc domain in microorganisms.
The present invention relates to a novel use of an immunoglobulin Fc fragment.
One is that certain immunoglobulin Fc domains participate in effector functions of the immune system.
Recombinant DNA technologies were applied to fuse a protein drug to an immunoglobulin Fc fragment.
Same amount of the purified human immunoglobulin Fc was injected into negative control mice.
Preferable is a hinge region which is the same in origin as the immunoglobulin Fc region.
In the present disclosure the immunoglobulin Fc can be interchangeably used with immunoglobulin fragment.
One of such technique is making a fusión protein with the immunoglobulin Fc fragment.
The immunoglobulin Fc region produced by the present invention includes an amino acid sequence derivative.
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Such a complex may be stabilized by disulfide bond formation between the immunoglobulin Fc domains.
Preferably, the immunoglobulin Fc region may be aglycosylated.
Fc receptors are molecules which bind specifically to active molecular sites within immunoglobulin Fc regions.
The immunoglobulin Fc polypeptide is modified to enhance FcRn binding ;.
The resulting nucleotide sequences encoding the recombinant immunoglobulin Fc regions are represented by SEQ.
As a result, immunoglobulin Fc was observed to be overexpressed in all of the transformants produced.
As a result, a very small amount of immunoglobulin Fc was detected.
In some cases, the immunoglobulin Fc domain is a human immunoglobulin Fc domain.
For example, a polypeptide is conjugated to an immunoglobulin Fc region.
In one case, the immunoglobulin Fc domain is from a mammal.
For example, a polypeptide may be conjugated to an immunoglobulin Fc region.
However, techniques employing an immunoglobulin Fc fragment as a drug carrier are unknown.
In some embodiments, the polypeptide may comprise an immunoglobulin Fc domain.
Preferably, the immunoglobulin Fc region may further include a hinge region.
The FcRn-binding material may be an immunoglobulin Fc region.
Optionally, the immunoglobulin Fc region may further comprise a hinge region.
Preferably, the carrier is an immunoglobulin Fc region.
Preferably, the immunoglobulin Fc region may be a human aglycosylated IgG4 Fc region.
In the present invention, the factors can be immunoglobulin Fc region.
Depending on the immunoglobulin Fc region, the hinge region to be fused may be chosen.
In some embodiments, the second polypeptide is part or whole of an immunoglobulin Fc region.
The immunoglobulin Fc receptor plays an important role in antibody-mediated immune response.
Within one embodiment, the polypeptide further comprises an immunoglobulin Fc polypeptide.
In the present invention, the immunoglobulin Fc can be interchangeably used with immunoglobulin fragment.
In a further embodiment, the chimeric peptide is fused with an immunoglobulin Fc region.
Specifically, the immunoglobulin Fc fragment of the present invention may be a hybrid immunoglobulin Fc fragment.
The insulin conjugate of claim 1, wherein the immunoglobulin Fc region is aglycosylated.
FIG . 2c is a graph showing the result of purifying conjugates including oxyntomodulin and immunoglobulin Fc.
For example, a polypeptide can be conjugated to an immunoglobulin Fc region or bovine serum albumin.
Immunoglobulin Fc fragment modified by non-peptide polymer and pharmaceutical composition comprising the same.
In another embodiment, the second amino acid sequence corresponds to an immunoglobulin Fc region.
Under certain circumstances, the immunoglobulin Fc region preferably lacks at least the CH, domain.
In a further embodiment, the polypeptide is a fusión protein further comprising an immunoglobulin Fc domain.
Preferably, a human-derived Fc region is a recombinant immunoglobulin Fc region that is obtained from a microorganism.
The nucleic acid molecule of claim 9 wherein the heterologous polypeptide comprises an immunoglobulin Fc fragment.
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