Examples of 'immunoglobulin genes' in a sentence
Meaning of "immunoglobulin genes"
immunoglobulin genes: These are genes that are responsible for producing proteins called immunoglobulins, also known as antibodies. These genes play a key role in the immune system's ability to recognize and attack foreign substances such as bacteria and viruses
How to use "immunoglobulin genes" in a sentence
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immunoglobulin genes
Nomenclature of the immunoglobulin genes is well known.
All results are representative of the other amplified immunoglobulin genes.
All or portions of immunoglobulin genes may be expressed.
Also envisaged are genetic variants of immunoglobulin genes.
The immunoglobulin genes are rearranged.
Several regulatory elements in immunoglobulin genes have been described.
Immunoglobulin genes mechanisms.
Biochemical mechanisms of mismatch repair during somatic hypermutation of immunoglobulin genes.
Transgenic mice containing human immunoglobulin genes are immunized with the antigen of interest.
These primers bind to the constant region of the immunoglobulin genes.
The chimeric immunoglobulin genes can be expressed in nonlymphoid cells such as bacteria or yeast.
A phage library can be prepared by using various immunoglobulin genes as sources.
Immunoglobulin genes have been extensively studied in order to identify sequences regulating gene expression.
The cell produces only immunoglobulin encoded by the transformed immunoglobulin genes.
Cloning and sequencing cynomolgus immunoglobulin genes has not been previously described in the literature.
See also
Other sources of human antibodies are transgenic mice engineered to express human immunoglobulin genes.
The mouse germline immunoglobulin genes coding for the antibody constant regions remain unchanged.
A naturally occurring immunoglobulin consists of one or more polypeptides substantially encoded by immunoglobulin genes.
Human immunoglobulin genes have been introduced into the mice to replace the inactivated mouse genes.
This cell line was grown up to larger numbers for cloning of its immunoglobulin genes.
Compositions and methods for inhibiting endogenous immunoglobulin genes and producing transgenic human idiotype antibodies.
Somatic hypermutation involves a programmed process of mutation affecting the variable regions of immunoglobulin genes.
A promising alternative is the modification of immunoglobulin genes by using recombinant DNA technology.
Such antibodies can be generated by immunizing transgenic animals which contain human immunoglobulin genes.
The immunoglobulin genes of the fetal ruminant ileal Peyer s patch can possibly be further modified.
The production of transgenic mice containing various forms of immunoglobulin genes has also been reported.
The immunoglobulin genes were expressed in mammalian cells to express the protein / antibody.
These cell lines produce only the immunoglobulin encoded by the transfected immunoglobulin genes.
After ligation, both immunoglobulin genes are serially cloned.
Part of this response involves the hypermutation of the variable portion of the immunoglobulin genes.
Indeed, several regulatory elements in immunoglobulin genes have been described.
Human antibodies can also be produced using transgenic mice that express human immunoglobulin genes.
In another embodiment, said immunoglobulin genes comprise immunoglobulin heavy genes.
Examination of the derived amino acid sequences revealed considerable homology with other characterised immunoglobulin genes.
In another embodiment, all or portions of immunoglobulin genes may be expressed.
Alternatively, chimeric immunoglobulin genes can be inserted in a cDNA configuration using heterologous viral promoter / enhancer sequences.
The production of transgenic mice containing various forms of immunoglobulin genes has been reported previously.
Using various types of immunoglobulin genes as sources, a phage library can be also created.
These techniques have also allowed the stable introduction of immunoglobulin genes into myeloma cells.
In another instance, said immunoglobulin genes comprise immunoglobulin heavy genes.
Specific examples of PCR assembly of human immunoglobulin genes.
Clonal rearrangements of the immunoglobulin genes ( heavy and light chains ) are frequently seen.
A human follicular lymphoma B cell line hypermutates its functional immunoglobulin genes in vitro.
The repertoire of rearranged immunoglobulin genes of an animal not immunised with complementary sbp member ;.
Plasmacytoma cells can synthesize, assemble and secrete immunoglobulins encoded by transformed immunoglobulin genes.
However, the functional inactivation of immunoglobulin genes presents many obstacles in many vertebrate species.
Preferred RNA splice sites may be obtained from adenovirus and / or immunoglobulin genes.
Inactivation of endogenous immunoglobulin genes preferably can be achieved, e.g., by targeted homologous recombination.
Suitable RNA splice sites may be obtained from adenovirus and / or immunoglobulin genes.
Transgenic mice containing human immunoglobulin genes are immunized with the antigen of interest, e.g., HGF.
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