Examples of 'monovalent antibody' in a sentence
Meaning of "monovalent antibody"
monovalent antibody - In the context of immunology, a monovalent antibody is an antibody that binds to a single specific antigen site. It is characterized by its ability to recognize and bind to a particular target molecule or pathogen with high specificity. Monoclonal antibodies are often used in research, diagnostics, and therapy to selectively target and neutralize specific antigens
How to use "monovalent antibody" in a sentence
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monovalent antibody
Both a bivalent antibody and a monovalent antibody are included.
Monovalent antibody fragments useful as therapeutics.
Method for rapidly radiolabelling monovalent antibody fragments with technetium.
Monovalent antibody fragments.
Another reason for developing monovalent antibody fragments derives from the target biology.
A monovalent antibody lacks the capacity to cross link molecules of a single antigen.
If such a receptor should be blocked, a monovalent antibody fragment is the natural format of choice.
A monovalent antibody may not have the same effectiveness as the bivalent parent molecule.
The bands can therefore be identified as bivalent antibody, monovalent antibody and Fc molecules respectively.
Monovalent antibody fragments as meant in the present invention have only one antigen binding site.
In further embodiments, the monovalent antibody is a humanized or a fully human antibody.
For example, an antibody can be reduced with dithiothreitol ( DTT ) to yield monovalent antibody fragments.
A monovalent antibody of claim 4 which is pegylated.
Sandwich ELISA of IgG1 type monovalent antibody.
A modified monovalent antibody fragment comprising a heavy chain and a light chain, wherein,.
See also
The method of claim 1, wherein the monovalent antibody is a heterodimer of,.
Preferably the monovalent antibody specifically binding to CD3 is a Fab fragment, preferably a CD3 crossFab.
The method of claim 2, wherein the monovalent antibody is pegylated.
Similarly to some monovalent antibody fragments, some SPCBP mixtures efficiently induce apoptosis.
The invention also provides an anti-CD154 antibody that is a monovalent antibody or monovalent antigen-binding fragment.
A monovalent antibody of claim 2, which is a heterodimer of,.
Further, the structures of various monovalent antibody molecules are shown in FIG . 5.
Antibody-dependent cytotoxicity of anti-CD20 monovalent antibody.
The method of claim 4, wherein said monovalent antibody fragment is a Fab or Fab ' fragment.
FIG . 12 shows the amount of HL heterodimer of IgG4 type monovalent antibody by sandwich ELISA.
Therefore, anti-HER2 monovalent antibody was found to specifically bind to HER2.
One non-limiting example of a monovalent antibody fragment is a F ( ab ' ) fragment.
For example, a monovalent antibody ( e.g., Fab ) has one binding site for a particular epitope.
The method of claim 1, wherein said monovalent antibody fragment is a Fab-SH or Fab ′ - SH fragment.
Scheme of the major byproduct - monovalent antibody monomer ( MoAb ) with CH1-CL crossover ( abbreviated MoAb ).
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Examples of using Monovalent
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Y represents a monovalent inorganic or monovalent organic anion
Such an approach was used in isolation of monovalent streptavidin
The role of monovalent metal ions is unnoticed
Examples of using Antibody
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Antibody status should be monitored and reported
The kinetics of antibody decline are also similar
Antibody persistence after booster immunisation adults
