Examples of 'multispecific antibody' in a sentence
Meaning of "multispecific antibody"
Multispecific antibody: This term refers to an antibody that can bind to multiple targets or antigens simultaneously, often used in medical research and treatments
How to use "multispecific antibody" in a sentence
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multispecific antibody
Such a multispecific antibody may be a bispecific antibody.
Method for the detection of a multispecific antibody.
The multispecific antibody is prepared by recombinant methods.
Multispecific antibodies include multispecific antibody fragments.
Multispecific antibody compositions can further comprise a therapeutic agent.
One embodiment of the invention relates to a trivalent multispecific antibody.
Recovering the multispecific antibody from the cell culture.
A polypeptide multimer of the present invention can be a multispecific antibody.
It may be desirable to generate a multispecific antibody comprising the monoclonal antibody.
In certain embodiments of the heteromultimer is provided a bispecific antibody or a multispecific antibody.
Recovering said multispecific antibody from said host cell culture.
Such an approach can also be used to prepare multispecific antibody compositions.
The multispecific antibody according to the invention is capable of binding to different epitopes.
In one embodiment of the invention the multispecific antibody is an isolated antibody.
The multispecific antibody can also be prepared in the same way as above.
See also
In one preferred embodiment of the invention the multispecific antibody is a bispecific antibody.
A multispecific antibody is a molecule having binding specificities for at least two different antigens.
Another object of the invention is a multispecific antibody produced by a method according to the invention.
A multispecific antibody according to any one of the preceding embodiments wherein the antibody is bispecific.
Another object of the invention is a pharmaceutical composition comprising a multispecific antibody according to the invention.
A multispecific antibody produced by the method according to claim 9.
Detailed description of the embodiments of the invention Multispecific antibody.
A multispecific antibody comprising one or more antibodies of claim 1.
A scheme of the general structure of said multispecific antibody is depicted in Fig.
Thereby, the multispecific antibody according to this embodiment is at least trispecific.
In some embodiments, the antibody is a multispecific antibody.
In an embodiment, a multispecific antibody molecule is a bispecific antibody molecule.
In some embodiments, the protein complex is a multispecific antibody.
In some examples, the multispecific antibody is a bispecific, trispecific or tetraspecific antibody.
In other embodiments, the antibody is a bispecific or multispecific antibody.
Thereby, the multispecific antibody according to this embodiment may be bispecific or trispecific.
In another such aspect, the multispecific antibody is labeled.
Specifically, a polypeptide multimer of the present invention can be a multispecific antibody.
The multispecific antibody according to embodiment 57 for use as in the treatment of cancer.
The antibody or binding fragment may be a monospecific, bispecific or multispecific antibody.
An example of a multispecific antibody is a " bispecific antibody " which binds two different epitopes.
One embodiment of the invention relates to a trivalent, trispecific multispecific antibody.
In one embodiment of the invention, the multispecific antibody is devoid of a hinge region.
One embodiment of the invention relates to a trivalent, bispecific multispecific antibody.
In an embodiment, a multispecific antibody molecule comprises a third, fourth or fifth immunoglobulin variable domain.
A host cell comprising nucleic acid encoding the multispecific antibody of claim 17.
The multispecific antibody is devoid of a CH2 domain.
Alternatively, multi-scFv comprising three or more scFvs may be used as a multispecific antibody.
In another such aspect, the multispecific antibody binds both TfR and Abeta.
A method according to claim 2 in which the antibody is a bispecific, trispecific or other multispecific antibody.
A multispecific antibody according to claim 25 which is a bispecific antibody.
Fragments of antibodies covalently coupled vía linker peptides, resulting in bispecific or multispecific antibody fragments ;.
A multispecific antibody comprising one or more antibodies of claims 1-8.
Thereby, chain mispairing is avoided and the expression yield of the multispecific antibody is improved.
The multispecific antibody according to embodiment 57 for use as a medicament.
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Examples of using Multispecific
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Such a multispecific antibody may be a bispecific antibody
Method for the detection of a multispecific antibody
Multispecific antibodies include multispecific antibody fragments
Examples of using Antibody
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Antibody status should be monitored and reported
The kinetics of antibody decline are also similar
Antibody persistence after booster immunisation adults
