Examples of 'nucleases' in a sentence
Meaning of "nucleases"
nucleases (verb) - Enzymes that cleave the phosphodiester bond between nucleotides in nucleic acids
Show more definitions
- plural of nuclease
How to use "nucleases" in a sentence
Basic
Advanced
nucleases
Nucleases split nucleic acids into nucleotides.
Patisiran is metabolized by nucleases to nucleotides of various lengths.
Nucleases are also extensively used in molecular cloning.
The one or more nucleases are RNases or ribonucleases.
Gene targeting using zinc finger nucleases.
A degradation by nucleases of the unhybridized nucleotide sequences.
These molecules have greater resistance to nucleases.
Other nucleases are well known in the art.
Such a duplex may be susceptible to degradation by nucleases.
Suitable nucleases for decellularization are commercially available.
There are several sources for single strand nucleases.
Such nucleases include endonucleases and exonucleases.
Oligonucleotides are subject to being degraded or inactivated by cellular endogenous nucleases.
Nucleases can hydrolyze nucleic acid phosphodiester bonds.
Use of thermophilic nucleases for degrading nucleic acids.
See also
Nucleases are a very diverse group of enzymes.
Phosphodiester bonds are attacked by a variety of nucleases.
Nucleases are known from numerous organisms.
The targeted modification was assisted by zinc finger nucleases.
Defects in certain nucleases can cause genetic instability or immunodeficiency.
Commercially available restriction nucleases were used.
The one or more nucleases may be mixed as a nuclease cocktail.
The oligonucleotide analogues obtained are resistant to various nucleases.
Nucleases may also serve a role in host defence mechanisms.
Enzymatic colicins typically act as nucleases in the cytoplasm.
Nucleases utilize a variety of nucleophiles to cleave a scissile phosphate bond.
Chemical modifications increase their stability towards nucleases.
Mung bean is known to contain nucleases as well as protease inhibitors.
Some nucleases have both endonuclease and exonuclease activities.
Zinc finger protein nucleases.
Other thermophilic nucleases can be tested for their suitability.
Molecular biology requiring the absence of endotoxins and nucleases.
The phosphorothioate analog is resistant to nucleases normally present in cells.
The imaging agent should also be resistant to degradation by nucleases.
Nucleases and ligases.
Such modified oligonucleotides are attractive because of increased stability to nucleases.
Particularly calcium sensitive nucleases seem to be responsible for this degradation.
The phosphodiester analogues are more resistant to attack by cellular nucleases.
Nucleases break down nucleic acids by hydrolyzing bonds between nucleotides.
The mutations or variation may be induced by engineered nucleases in cells.
Nucleases can be removed from extracts to help stabilize mRNA levels.
The present invention employs nucleases to remove contaminating nucleic acids.
Nucleases were most likely to have originated from the blood specimen.
And the simplest nucleic acids or nucleotides are broken down by nucleases.
These include nucleases dependent upon ions such as magnesium and calcium.
The linear oligonucleotides are rapidly degraded by the nucleases in the serum.
There remains a need for nucleases that will facilitate precise modification of a genome.
Phosphodiesters are cleaved by nucleases.
Such phosphorothioate linkages are resistant to nucleases and so improve stability of the oligonucleotide.
The viroplasm could also prevent virus degradation by proteases and nucleases.
