Examples of 'nucleobase' in a sentence
Meaning of "nucleobase"
nucleobase: The building blocks of nucleic acids such as DNA and RNA, consisting of adenine, thymine (or uracil in RNA), cytosine, and guanine
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- The base of a nucleic acid, such as thymine, uracil, adenine, cytosine and guanine.
How to use "nucleobase" in a sentence
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nucleobase
Adenine is a nucleobase synthesized by the human body.
One group exploited the nucleobase adenine.
The nucleobase may be a pyrimidine or derivative thereof.
Each of those differences is referred to as a differentiating nucleobase.
Adenine is a nucleobase that comes from purines.
Individual nucleosides are made by attaching a nucleobase to a ribose sugar.
Such nucleobase pairs are said to be complementary to one another.
A vast number of nucleobase analogues exist.
A nucleobase can be naturally occurring or synthetic.
Equivalent amounts of other nucleobase sources may be used.
These nucleobase changes can produce novel proteins.
Nucleosides are glycosylamines made by attaching a nucleobase to a ribose ring.
Glycosylation of the nucleobase with an appropriately modified sugar.
Nucleobase residues may be members of oligomers and probes.
Each instance of the nucleobase is independently blocked or unblocked.
See also
A cEt nucleoside may comprise a modified or unmodified nucleobase.
In one embodiment the nucleobase linkages are all phosphodiester.
In some instances a mimetic is used in place of the nucleobase.
This is because certain nucleobase salts are moisture sensitive.
The nucleobase protecting group in each example is trimethylsilyl.
A bicyclic nucleoside may have a modified or unmodified nucleobase.
This is because certain nucleobase derivatives are moisture sensitive.
The antisense compound may comprise a modified nucleobase.
The substructure consisting of a nucleobase plus sugar is termed a nucleoside.
Nucleobase oligomers may also include nucleobase modifications or substitutions.
A nucleoside is a compound comprising a nucleobase and a sugar group.
The modified nucleobase for example can be the thymine.
Methylguanine is a modified purine nucleobase.
Nucleobase transport proteins.
Particularly preferred subunits for compomer polymerization are nucleobase subunits.
The nucleobase and the sugar constitute a unit referred to as a nucleoside.
The ligand is typically a nucleobase.
These nucleobase cation salts are prepared by adding a base to the nucleobase in a solvent.
The dye may be conjugated to either the sugar or nucleobase.
One nucleotide contains an adenine nucleobase and the other nicotinamide.
One embodiment of the invention is therefore to include a modified nucleobase.
Oligonucleotides of the invention may also include nucleobase modifications or substitutions.
A modified nucleoside may have a modified sugar and an unmodified nucleobase.
A linked polymer comprises two or more nucleobase sequences which are linked by a linker.
Nucleosides and nucleotides may be labelled at sites on the sugar or nucleobase.
Nucleobase oligomers may also contain one or more substituted sugar moieties.
Nucleotides are a preferred nucleobase.
Preferably the probing nucleobase sequence hybridizes to the entire target sequence.
The linker is preferably coupled to a non nucleobase part of the probe.
The probing nucleobase sequence is complementary or substantially complementary to a target sequence of interest.
A modified nucleoside may have a modified sugar and a modified nucleobase.
The present invention also includes nucleobase oligomers that are chimeric compounds.
The oligonucleotides can include chemical modifications to their nucleobase constituents.
Certain nucleobase modifications increase the binding affinity of the compounds of the invention.
Complementary oligomeric compounds need not have nucleobase complementarity at each nucleoside.
