Examples of 'modified nucleobase' in a sentence
Meaning of "modified nucleobase"
modified nucleobase: A altered form of a building block of DNA or RNA
How to use "modified nucleobase" in a sentence
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modified nucleobase
The antisense compound may comprise a modified nucleobase.
The modified nucleobase for example can be the thymine.
One embodiment of the invention is therefore to include a modified nucleobase.
In certain embodiments, a modified nucleobase comprises a polycyclic heterocycle.
A modified nucleoside may have a modified sugar and a modified nucleobase.
In certain embodiments, a modified nucleobase comprises a tricyclic heterocycle.
In one embodiment the ORN further comprises at least one modified nucleobase.
In some embodiments, the modified nucleobase is a modified guanine.
Ba represents a nucleobase, which is a natural or modified nucleobase.
In some embodiments, the modified nucleobase is a modified cytosine.
In certain embodiments, at least one nucleoside comprises a modified nucleobase.
In some embodiments, the modified nucleobase is a modified uracil.
Modified nucleosides comprise a modified sugar moiety and / or a modified nucleobase.
In certain embodiments, a modified nucleobase comprises a phenoxazine derivative.
In certain embodiments, oligonucleotides comprise one or more nucleosides comprising a modified nucleobase.
See also
The oligonucleotides may have modified sugar components, modified nucleobase components or modified internucleotide linkages.
Such modified nucleosides may include a modified sugar and / or a modified nucleobase.
Probes may include modified nucleobase residues and modified intra-nucleobase bonds in any combination.
In certain embodiments, at least one nucleoside of the modified oligonucleotide comprises a modified nucleobase.
In certain embodiments, the modified nucleobase is 5-methylcytosine.
In certain embodiments, the compound has at least one nucleoside comprising a modified nucleobase.
The modified nucleobase may be a 5-methylcytosine.
In certain embodiments, at least one nucleoside of said modified oligonucleotide comprises a modified nucleobase.
At least one modified nucleobase, wherein optionally the modified nucleobase is a 5-methylcytosine.
In certain embodiments, the antisense compound comprises at least one nucleoside comprising a modified nucleobase.
For example, a modified nucleobase can be 5 ′ - methylcytosine.
In certain embodiments, oligonucleotides having a gapmer sugar motif comprise a nucleoside comprising a modified nucleobase.
In certain instances, the modified nucleobase is 5-methylcytosine.
For example, a modified nucleoside or nucleotide can have a modified sugar and a modified nucleobase.
In some embodiments, the modified nucleobase is 5-methylcytosine.
The single-stranded modified oligonucleotide of claim 1, wherein at least one nucleoside comprises a modified nucleobase.
In certain embodiments, the said modified nucleobase is a 5 ' - methylcytosine.
Ba is a blocked or unblocked adenine, cytosine, guanine, thymine, uracil or modified nucleobase.
Comprises a modified nucleobase, optionally wherein the modified nucleobase is a 5-methylcytosine ; and / or.
The compound for use according to claim 6, wherein the modified nucleobase is a 5-methylcytosine.
In certain embodiments, a modified nucleobase is selected from 5-hydroxymethyl cytosine, 7-deazaguanine and 7-deazaadenine.
A “ modified nucleoside ” means a nucleoside having, independently, a modified sugar moiety or modified nucleobase.
The single-stranded modified oligonucleotide of claim 2, wherein the modified nucleobase is a 5-methylcytosine.
For example, 5-methylcytosine is a modified nucleobase.
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Examples of using Nucleobase
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Adenine is a nucleobase synthesized by the human body
One group exploited the nucleobase adenine
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