Examples of 'ospc' in a sentence
Meaning of "ospc"
OSPC stands for Ontario Society for the Prevention of Cruelty to Animals, an organization dedicated to animal welfare and advocacy in the Canadian province of Ontario
How to use "ospc" in a sentence
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ospc
At present no typing system exists for OspC.
Truncated OspC genes were generated using other primers.
The second sequence can encode a an OspC antigen.
The production of OspC was examined in continuous fermentation run.
Purification of recombinant OspC.
The OspC product is cloned into a suitable vector.
Large scale production of OspC protein in the fermenter.
The OspC binds to the column.
Preferred combinations include all or a portion of OspC linked to all or a portion of OspA.
The OspC product was cloned into a suitable vector.
The chimeric polypeptides described herein elicit specific immune responses to OspC.
The OspC polypeptide portion does not include a lipidation signal.
The human isolates were distributed evenly throughout the various OspC families.
Sequences for the OspC types had been identified previously.
A vaccine that includes one or more of these four forms of OspC is described.
See also
All ospC groups were found more or less commonly in ticks.
This analysis has been used to assign the OspC proteins into OspC families.
Expression of OspC was induced by the presence of methanol in the growth medium.
The chimeric polypeptides of the present invention elicit specific immune responses to OspC.
Homogenous OspC may be comprised of more than one serological form of OspC.
The sequence information has been used to classify OspC proteins into OspC families.
Animals are vaccinated with OspC and serum with high levels of borreliacidal activity are collected.
The hypothesis was that the spirochete must need OspC to survive in a new host.
OspC plays an essential role during the early stage of mammalian infection.
These chimeric proteins have the general structure of OspC linked to OspA vía a peptide bond.
Serotyping of the OspC proteins was performed using a standard membrane ELISA technique.
The chimeric polypeptides of the present invention elicit specific immune responses to OspC and OspA.
These results demonstrate that vaccination with OspC may be more effective than vaccinations with OspA.
OspC protein concentration was determined by the method of Bradford.
Vanguard has developed a vaccine that combines chunks of seven different OspC proteins along with OspA.
Cloning and Sequencing of OspC Similar methods were also used to isolate OspC genes.
Construction of the Pichia pastoris OspC expression vector.
OspA and OspC share many characteristics.
Cloning and Amplification of the ospC Gene.
The purified PCR fragment containing the OspC coding seuqence was ligated with the vector overnight.
The OspC peptides described in US Pat.
In this embodiment, a lipidated OspC or OspC chimeric protem is produced.
Thus, ospC is a good marker for human pathogenicity and perhaps its determinator.
In this embodiment, a lipidated OspC or OspC chimeric protein is produced.
Thus, the OspC heterogeneity will not hinder efforts to develop a comprehensive OspC vaccine.
Therefore, three categories of major ospC groups are defined herein.
DNA sequencing The ospC gene or representatives of each mobility class were reamplified.
Alternatively, the chimeric protein comprises two or more OspC variable polypeptides as described above.
Furthermore, the OspC gene has been discovered to be clonally inherited.
Further, the invention comprises the recombinant preparation of novel OspC antigens as shown in Figure 9a.
Thus, a lipidated OspC or OspC chimeric protein is produced.
The dendrogram showing the phylogenetic relationship between the OspC protein is presented in Figure 10.
The number of each major ospC group observed in blood, synovial fluid or cerebrospinal fluid.
ELISA testing was performed on these será using purified non-lipidated OspC as the coating antigen.
Mice vaccinated with recombinant OspC do, in fact, produce borreliacidal antibodies.
