Examples of 'phosphodiester bonds' in a sentence
Meaning of "phosphodiester bonds"
phosphodiester bonds: These are chemical bonds that form the backbone of DNA and RNA molecules, providing structural stability and allowing genetic information to be stored and transmitted
How to use "phosphodiester bonds" in a sentence
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phosphodiester bonds
Saccharides comprising phosphodiester bonds are unstable to hydrolysis.
Usually nucleosidic monomers are linked by phosphodiester bonds.
All or part of the phosphodiester bonds are advantageously protected.
Nucleases can hydrolyze nucleic acid phosphodiester bonds.
Saccharides comprising phosphodiester bonds may be unstable to hydrolysis.
Phosphodiester bonds are attacked by a variety of nucleases.
In some embodiments the linkages include phosphodiester bonds.
By phosphodiester bonds through the.
Each strand is a chain of nucleosides linked by phosphodiester bonds.
Exonucleases may cleave the phosphodiester bonds at blunt ends or sticky ends.
In various embodiments all the covalent bonds are phosphodiester bonds.
Other modified phosphodiester bonds or bond analogs are well known in the art.
In another embodiment the mixed duplex oligonucleotide is linked by unsubstituted phosphodiester bonds.
Polynucleotide monomers can be linked by phosphodiester bonds or analogs of such linkages.
Naturally occurring nucleic acids generally have a backbone containing phosphodiester bonds.
See also
Nucleic acid monomers can be linked by phosphodiester bonds or analogs of such linkages.
The backbone of the primer is not restricted to those composed of phosphodiester bonds.
Additionally or alternatively the phosphodiester bonds of the nucleic acid can be replaced by phosphorothiodiesters.
Primary structure consists of a linear sequence of nucleotides that are linked together by phosphodiester bonds.
Phosphodiester bonds or phosphothioate bonds may link the nucleotides of the ligation splints.
The native capsular saccharide may comprise saccharide units linked by phosphodiester bonds.
The phosphodiester bonds may be substituted with structures that are chiral and enantiomerically specific.
These motifs participate in the coordination of metal ions and hydrolysis of phosphodiester bonds.
Several agents are known which cleave the phosphodiester bonds in nucleic acids at abasic sites.
Phosphodiester bonds or phosphothioate bonds may link the nucleotides or nucleotide analogs of the linkers.
The nucleotides combine with each other by covalent bonds known as phosphodiester bonds or linkages.
Phosphodiester bonds make up the backbone of the strands of DNA and RNA.
Phosphoramidites are linked together into a single strand nucleic acid polymer through phosphodiester bonds.
This complex permits hydrolysis of the phosphodiester bonds of DNA and of RNA.
The recombinagenic oligonucleobase is a mixed duplex oligonucleotide that is linked solely by unsubstituted phosphodiester bonds.
The nucleotides may be linked by phosphodiester bonds or non-hydrolyzable bonds.
The backbone structure of TNA comprises repeating threose sugars linked by phosphodiester bonds.
Likewise, phosphodiester bonds may be transformed to uncharged derivatives employing trialkylsilyl chlorides.
Benzonase rapidly disintegrates nucleic acid by hydrolyzing internal phosphodiester bonds between specific nucleotides.
Cleave To break phosphodiester bonds of double-stranded DNA, usually with a type II restriction endonuclease.
The present invention provides that oligonucleotides with other than phosphodiester bonds may be used.
Typically, a polynucleotide is formed through phosphodiester bonds between the individual nucleotide monomers.
Ribozymes are RNA molecules which catalyse the cleavage and formation of phosphodiester bonds.
A hydrolyzing reaction that breaks phosphodiester bonds at either the 3 ' or the 5 ' end occurs.
DNA is composed of nucleotides that are joined by phosphodiester bonds.
The Trex2 enzyme specifically hydrolyzes the phosphodiester bonds which are exposed at 3 ' overhangs.
Nucleases are enzymes that cut DNA strands by catalyzing the hydrolysis of the phosphodiester bonds.
Nucleotide multimer, a chain of nucleotides linked by phosphodiester bonds or analog thereof.
By “ nucleic acid ” is meant a succession of nucleotides joined together by phosphodiester bonds.
Examples of covalent bonds include, but are not limited to, phosphodiester bonds and phosphorothioate bonds.
In another example, the mixed duplex oligonucleotide is linked by unsubstituted phosphodiester bonds.
The phosphorolytic enzymes use inorganic phosphate to cleave the phosphodiester bonds - releasing nucleotide diphosphates.
An " oligonucleotide " refers to multiple nucleotides linked by phosphodiester bonds.
As with all endonucleases, Benzonase ® hydrolyzes internal phosphodiester bonds between specific nucleotides.
Preferably, the linker will be composed of ordinary nucleotides joined by phosphodiester bonds.
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Examples of using Phosphodiester
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All phosphodiester groups are replaced methylphosphonate groups
This may derive from deoxyribose phosphodiester
All phosphodiester groups are replaced by phosphorothioate groups
