Examples of 'plasma half-life' in a sentence
Meaning of "plasma half-life"
Plasma half-life refers to the time it takes for the concentration of a substance in the blood plasma to decrease by half. This is commonly used in pharmacology and medicine to determine how long a drug remains in the body
How to use "plasma half-life" in a sentence
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plasma half-life
The plasma half-life of imipenem was one hour.
Guaifenesin has a plasma half-life of one hour.
The plasma half-life of cilastatin is approximately one hour.
Its duration of action is reflected by its plasma half-life.
Their plasma half-life is approximately three weeks.
Furthermore ranolazine also has a relatively short plasma half-life.
Its plasma half-life increases with the dose.
The depletion from tissues was consistent with the plasma half-life.
The plasma half-life for isoprenaline is approximately two minutes.
Guaifenesin has a typical plasma half-life of approximately one hour.
The plasma half-life of montelukast is slightly longer in the elderly.
In some embodiments the second and first plasma half-life are similar.
Plasma half-life is about six weeks after a single intramuscular injection.
Preferably the intrinsic plasma half-life of the polypeptide itself is increased.
A one-phase exponential decay curve fit was used to calculate the plasma half-life.
See also
Natural tPA has a plasma half-life of about six minutes or less.
In yet another aspect, the antidote is conjugated with a moiety to extend its plasma half-life.
An improvement in plasma half-life would bring significant benefit to the patient.
Another approach is to increase the intrinsic plasma half-life of the polypeptide itself.
The apparent plasma half-life of pentosan polysulfate sodium depends on the route of administration.
In volunteers with reduced renal function, the plasma half-life of cefotetan is prolonged.
Determination of the plasma half-life and placental transfer are performed by well established techniques.
The resulting PEGylated peptides demonstrated significantly increased plasma stability and prolonged plasma half-life in mice.
The mean elimination plasma half-life of mefloquine is between two and four weeks.
Some novel properties for facilitating purification and extending the plasma half-life time should be introduced.
Evidence suggests that the plasma half-life of vidarabine is increased in the presence of allopurinol.
The present invention overcomes the problems associated with delivering a compound that has a short plasma half-life.
From the second phase, the terminal plasma half-life of a DARPin can be determined.
The plasma half-life is prolonged if the patient is suffering from liver and renal insufficiency.
Examples on the determination of terminal plasma half-life are given in the Examples.
The mean plasma half-life of a sedative-hypnotic compound may be determined using well known techniques.
PEGylation may improve the solubility and plasma half-life of a peptide.
The plasma half-life of angiotensin II administered intravenously is less than one minute.
The PEG moiety is conjugated to octocog alfa to increase the plasma half-life.
The effect of glycosylation on plasma half-life and protein activity has also been extensively studied.
Apparent volume of distribution, clearance and plasma half-life.
Indocyanine green has a very short plasma half-life and is rapidly taken up by the liver D.
The plasma half-life of perindopril is equal to 1 hour.
Such modification allows an increasing of the plasma half-life time of the original PHC molecule.
The plasma half-life is about five days.
Determination of the Plasma Half-Life of GDXa and Xa.
The plasma half-life of levetiracetam in adults is about 6 to 8 hours.
Salicylic acid in DuoPlavin has a plasma half-life of approximately 2 hours.
The mean plasma half-life of lumiracoxib is approximately 4 hours.
The half-life is preferably a human serum or plasma half-life.
The terminal plasma half-life is approximately 2 weeks in dogs.
Note that biological half-life is different than plasma half-life.
The steady state plasma half-life of eflornithine was approximately 8 hours.
Temoporfin is a low clearance substance with a terminal plasma half-life of 65 hours in patients.
It has a short plasma half-life of about 1h after parenteral administration.
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Examples of using Plasma
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Plasma concentrations are similar in males and females
Operating the plasma display basic operations
Plasma concentrations were quantifiable in all the patients
Examples of using Half-life
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The half-life was prolonged in these patients
There is no change in half-life during treatment
Each elimination phase determines a half-life