Examples of 'receptor tyrosine kinase' in a sentence
Meaning of "receptor tyrosine kinase"
Receptor tyrosine kinase refers to a type of cell surface receptor protein involved in the transmission of signals within cells. These receptors play a crucial role in regulating various cellular processes, including growth, development, and metabolism. They are activated by specific ligands and initiate signaling cascades that can lead to changes in gene expression or cellular behavior. Receptor tyrosine kinases are implicated in numerous biological processes and are important targets for drug development
How to use "receptor tyrosine kinase" in a sentence
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receptor tyrosine kinase
And receptor tyrosine kinase inhibitors.
Novel approaches for ErbB receptor tyrosine kinase inhibition.
Thus receptor tyrosine kinase activity initiates a cellular signalling pathway leading to proliferation.
Such modulators may be candidate receptor tyrosine kinase modulators.
The disclosed compounds affect vascular leakage or pathological neovascularization by inhibiting a receptor tyrosine kinase.
The cMet receptor is part of the receptor tyrosine kinase family of signaling molecules.
The Axl receptor tyrosine kinase induced disorders are selected from a group comprising hyperproliferative disorders.
No mutations were detected in amplicons from other receptor tyrosine kinase genes.
ALK is a receptor tyrosine kinase identified for the first time by Morris et al.
The antagonists may be coadministered with a second receptor tyrosine kinase antagonist.
The RET receptor tyrosine kinase is a versatile receptor which responds to multiple signalling cues.
The cellular responses likely are typically mediated through receptor tyrosine kinase pathways.
IRSs are activated by insulin receptor tyrosine kinase that phosphorylates tyrosine residues of IRSs.
Each PRO polypeptide described herein is a receptor tyrosine kinase.
Tie-2 is a receptor tyrosine kinase found almost exclusively in endothelial cells.
See also
CMET kinase is also a receptor tyrosine kinase.
Flt3 receptor tyrosine kinase activity is implicated in leukemias and myelodysplastic syndrome.
It acts as an inhibitor of AXL receptor tyrosine kinase.
Evaluating statins and receptor tyrosine kinase inhibitors as a novel combinational anti-cancer therapeutic approach.
The RET protein is a transmembrane receptor tyrosine kinase.
ROS1 kinase is a receptor tyrosine kinase with an unknown ligand.
The cDNA encodes a novel type III receptor tyrosine kinase.
RET is a receptor tyrosine kinase identified as one of the proto-oncogenes.
They are ligands for the Eph receptor tyrosine kinase family.
A receptor tyrosine kinase ( RTK ) is a transmembrane protein that participates in transmembrane signaling pathways.
Antibodies binding to the extracellular domain of the receptor tyrosine kinase ALK.
A particularly preferred VEGF receptor tyrosine kinase inhibitor may be selected from,.
Perhaps the most promising drugs for treating fibrosis are the PDGF receptor tyrosine kinase inhibitors.
Molecular genetics of eph receptor tyrosine kinase signaling in C. elegans cell movements and axon guidance.
Exemplary VEGF receptor antagonists include inhibitors of VEGF receptor tyrosine kinase activity.
One receptor tyrosine kinase signaling pathway includes the vascular endothelial growth factor ( VEGF ) receptor kinase.
Staurosporin is the most potent PDGF receptor tyrosine kinase inhibitor previously described.
The formation of neuromuscular synapses requires the muscle-specific receptor tyrosine kinase MuSK.
Compounds which inhibit the VEGF receptor tyrosine kinase are those of formula I wherein.
The present invention provides compounds having the structure I which are VEGF receptor tyrosine kinase inhibitors.
Most preferably, the receptor tyrosine kinase is bFGF.
Fibroblast growth factor receptors ( FGFRs ) are kinases belonging to the receptor tyrosine kinase family.
In another embodiment, the receptor tyrosine kinase is a PDGFR kinase.
These receptors can include cytokine receptors, serpentine receptors, and receptor tyrosine kinase.
RET RET encodes a receptor tyrosine kinase.
These antibodies may also block the function of a protein called a muscle-specific receptor tyrosine kinase.
Pharmaceutical composition for delivery of receptor tyrosine kinase inhibiting ( rtki ) compounds to the eye.
In a still further aspect, the protein kinase that is inhibited is AXL receptor tyrosine kinase.
Preferred diseases involving deregulated FLT3 receptor tyrosine kinase activity are leukemias and myelodysplastic syndrome.
The preferred RTKi for use in the present invention is a multi-targeted receptor tyrosine kinase inhibitor.
Use of a PDGF receptor tyrosine kinase inhibitor of the formula I, wherein.
In some embodiments, the protein kinase is a receptor tyrosine kinase.
Receptor tyrosine kinase gene expression Receptor tyrosine kinase gene expression was characterized by RT-PCR.
These compounds are also Class I receptor tyrosine kinase inhibitors.
Certain pyrazine derivatives are selective inhibitors of vascular endothelial growth factor ( VEGF ) receptor tyrosine kinase.
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Examples of using Receptor
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Receptor is not sensitive to the type of change
Is that why that receptor network existed
This receptor can exist in three conformations
Examples of using Kinase
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Creatine kinase can be checked if myalgias develop
Blood tests show elevated creatine kinase
Elevation of creatine kinase in blood is indicative of myositis
Examples of using Tyrosine
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Tyrosine must be determined in hydrolysates of unoxidised samples
The protein possesses tyrosine kinase activity
Tyrosine hydroxylase can also be regulated by inhibition
