Examples of 'sialyl' in a sentence
Meaning of "sialyl"
sialyl (noun): A term related to biochemistry and glycobiology, referring to a type of sugar molecule. Sialyl groups are often found in glycoproteins and play important roles in various cellular functions
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- Of or pertaining to sialic acid or its derivatives
- A univalent radical derived from sialic acid
How to use "sialyl" in a sentence
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sialyl
These sialyl transferases are well known.
The antibodies can be subjected to sialyl transferases in vitro or in vivo.
These sialyl transferases are well know.
The pharmaceutical compositions are comprised of compounds which comprise a sialyl galactoside unit.
The addition of the sialyl machinery is also in process.
A sialyl transferase specifically adds sialyl groups onto a glycoprotein.
The invention also provides sialyl lactose preparations of very high purity.
This suggests that these strains arose via recombination of the sialyl transferase gene.
The produced sialyl galactoside can be used without purification.
Manganese ion is a required cofactor for at least one enzyme in the sialyl transferase cycle.
Entry sialyl phosphate donor.
Such products include sialyl Lewis ligands.
Sialyl lactose has also been investigated for the treatment of arthritis and related autoimmune diseases.
This particular type of EPO contains the Lewis x as well as the sialyl Lewis x structures.
For the production of sialyl lactose, the acceptor is lactose.
See also
A sialyl phosphate donor compound for synthesis of sialosides comprising,.
Schematic representation of Lewis x and Sialyl Lewis x structures.
In addition, sialyl lactose is useful as food supplement, for instance in baby formula.
Cells expressing sLex or sialyl di-Lex are then selected.
The plant of any preceding claim, further comprising a sialyl transferase.
The enzyme may include a sialyl transferase or a trans-sialidase.
After release from the resin, the glycopeptides obtained may be modified by a sialyl transferase.
The use according to claim 1, wherein the sialyl lactose is substantially purified.
A sialyl phosphate donor compound for synthesis of sialosides wherein the compound has the structure,.
Using these strategies, several biologically significant sialyl glycans have been synthesized.
Using the above protocol, a sialyl transferase substrate carrying a hydrophobic side chain was prepared.
In particular, the invention relates to synthesis of disialides using novel sialyl phosphate donor compounds.
Transferrin generally occurs in sialylated forms i.e. carrying three or more sialyl residues.
Sialyl Lewis x is also an inflammation-associated antigen on liver cells.
In some aspects, the method comprises separating sialyl a-phosphate from sialyl-Bphosphate by a process comprises chromatography.
Sialyl Lewis x was formed with a yield of about 30 percent as determined by scintillation counting.
The method preferably utilizes a partially purified sialyl transferase ( ST ) in this affinity step.
Sialidases, and their sialyl substrates, appear to be absent from plants and most other metazoans.
This glycoform can also be defined as biantennary glycan with sialyl Lewis x ( Lex ) antenna.
Alpha-selective sialyl phosphate donors for preparation of sialosides and sialoside arrays for influenza virus detection.
The use according to claim 32 wherein said composition comprises a sialyl Lewis X antigen.
Other possible structures include difucosyl sialyl Lex, a longer polyfucosylated polyactosaminoglycan, or a related variant.
The pharmaceutical composition according to claim 16 in which the Lewis X antigen is a sialyl Lewis X antigen.
Substrate specificity, Several classes of sialyl glycoconjugates were tested as substrates, TABLE II.
Key words, glycosyltransferases, pentadecasaccharide, sialyl Lewisx.
Defective synthesis of the sialyl Lewis X antigen results in immunodeficiency leukocyte adhesion deficiency type 2.
In a more preferred embodiment, the CR1 protein and the sialyl Lewis X antigen is used.
The modified sialyl moiety is added using ST3Gal-III.
The cell of claim 7, further comprising a sialyl transferase.
The sialyl polysaccharides bind to influenza virus hemagglutinin ( HA ) proteins.
The targeting construct according to claim 14, wherein said O-glycan moiety comprises a sialyl Lewis x structure.
However, other sialyl gangliosides tested were poor substrates ( Table I ).
These ligands include the naturally occurring ligands sialyl Lex ( SLex ) and sialyl Lea ( SLea ).
The effector is sialyl Lewisx recognized by ELAM-1 ( Phillips ).
This work describes the synthesis of novel sialyl Lewis X ( sLex ) analogues.
