Examples of 'variable domains' in a sentence
Meaning of "variable domains"
Variable Domains: In the context of mathematics or computer science, this phrase refers to the sets of possible values that variables can take on. It relates to the scope or range of valid inputs for a variable
How to use "variable domains" in a sentence
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variable domains
However the variable domains were not complementary.
Stable formulations of immunoglobulin single variable domains.
Single immunoglobulin variable domains are prepared in a number of ways.
Nucleotide sequences of rat antibody variable domains.
Antibody single variable domains against serum albumin.
Together these make up the variable domains.
Variable domains are also referred herein as variable regions.
Various aspects encompass light chain variable domains.
Variable domains may have any shape or form.
Various embodiments encompass light chain variable domains.
The two variable domains bind their specific antigens.
The epitope or antigen specificity of the variable domains is different.
The variable domains of the mouse and chimeric antibodies are identical.
Engineered rabbit antibody variable domains and uses thereof.
Method for the production of immunoglobulin single variable domains.
See also
These units contain variable domains and constant domains.
The present invention relates to formulations of single variable domains.
In an scFv two variable domains are connected to each other by a peptide linker.
The preparation of single immunoglobulin variable domains is described below.
The two variable domains bind the epitope on specific antigens.
Proteinaceous binding molecules comprising purification tags or inert variable domains.
Variable domains may be combined using methods other than linkers.
Pulmonary administration of immunoglobulin single variable domains and constructs thereof.
Full length variable domains were then cloned into mammalian expression vectors.
The maximum concentration of immunoglobulin single variable domains in liquids is limited.
Cloning immunoglobulin variable domains for expression by the polymerase chain reaction.
Stable formulations of immunoglobulin single variable domains and uses thereof.
Immunoglobulin single variable domains are added to the solid carrier in a liquid state.
Little is known about suitable formulations of immunoglobulin single variable domains.
This approach utilizes two antibody variable domains arranged on a single polypeptide.
An antigen binding domain may be provided by one or more antibody variable domains.
Blinatumomab consists of four immunoglobulin variable domains assembled into a single polypeptide chain.
In some cases it might be desirable to strengthen the association of two variable domains.
The variable domains and specific CDRs of representative monoclonal antibodies are described above.
The first and second engineerd domains are not antibody variable domains.
Variable domains may be attached to effector groups using methods other than linkers.
Methods for humanizing immunoglobulin single variable domains are known in the art.
The variable domains of the heavy and light chains function together in antigen binding.
Method for producing solid formulations comprising immunoglobulin single variable domains.
The cDNAs encoding heavy and light chain variable domains are isolated from a hybridoma.
Heavy and light chains are indeed composed of constant and variable domains.
Such a fragment contains only the variable domains of light and heavy chains of an antibody.
First a synthetic gene is designed to embody each of the synthetic variable domains.
The immunoglobulin single variable domains comprised within a multivalent construct may be identical or different.
The present disclosure encompasses suitable fragments of immunoglobulin single variable domains.
The expressed variable domains may be separate and not associate to form a multimeric protein.
In one embodiment the enzymatic sequences replaces one or multiple variable domains.
Genes encoding variable domains can be derived from hybridoma cDNA or from the chromosome.
Bivalent and bispecific antibodies can be constructed using only antibody variable domains.
These humanized heavy and light variable domains were termed hVH and hVL respectively.
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