Examples of 'antisense oligomer' in a sentence
Meaning of "antisense oligomer"
Antisense oligomer: A short piece of DNA or RNA that is complementary to a target gene's mRNA sequence. It can bind to the mRNA and inhibit gene expression, serving as a potential therapeutic approach for treating genetic disorders or diseases
How to use "antisense oligomer" in a sentence
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antisense oligomer
The antisense oligomer is chemically linked to a polyethylene glycol molecule.
The invention further encompasses the use of a short period of administration of a bcl-2 antisense oligomer.
Antisense oligomer Nucleotide sequence.
All caused exon 53 skipping with a higher efficiency than the antisense oligomer PMO No.
The antisense oligomer according to claim 6, which is a phosphorodiamidate morpholino oligomer.
The method of para 13 wherein said probe is an antisense oligomer.
The antisense oligomer according to paragraph 6, which is a phosphorodiamidate morpholino oligomer.
In a specific embodiment, the dose of a bcl-2 antisense oligomer is a high dose.
The antisense oligomer according to claim 1, wherein the antisense oligomer is a morpholino oligomer.
In one embodiment of the invention, a bcl-2 antisense oligomer is administered at high doses.
The antisense oligomer according to paragraph 1, which is an oligonucleotide.
In another specific embodiment, TGF-B is blocked by an antisense oligomer.
Then, the resulting antisense oligomer analog is purified using a reversed phase column.
FIG . 1B shows a conjugate of an arginine-rich peptide and an antisense oligomer.
The antisense oligomer according to claim 1, which is an oligonucleotide.
See also
Lanes 1, 2, cells unexposed or exposed to RIa antisense oligomer.
The antisense oligomer according to [ 6 ] above, which is a phosphorodiamidate morpholino oligomer.
The method of claim 5 or 6, wherein the antisense oligomer is a phosphorodiamidate morpholino antisense oligomer.
The antisense oligomer according to any one of claims 1 to 8, which is an oligonucleotide.
In another embodiment, a bcl-2 antisense oligomer is administered in combination with a regimen of radiation.
The antisense oligomer treatment regimen may be adjusted dose, frequency, route, etc.
In yet another embodiment, the bcl-2 antisense oligomer is comprised entirely of phosphorothioate linkages.
An antisense oligomer which consists of a nucleotide sequence of SEQ ID NO, 1 or 2 ; and.
In yet another embodiment, a bcl-2 antisense oligomer is used in association with a hormonal treatment.
FIG . 13 shows antisense oligomer penetration and stability in cultured corneas for up to one hour.
In one embodiment, the bcl-2 antisense oligomer is a hybrid oligomer containing phosphorothioate bases.
The antisense oligomer according to [ 1 ] above, which is an oligonucleotide.
In another embodiment, the bcl-2 antisense oligomer contains at least one phosphorothioate linkage.
An antisense oligomer comprising a nucleotide sequence of SEQ ID NO, 1 or 2 ;.
The antisense oligomer SEQ ID NO, 17 is DNA, or a derivative thereof.
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Examples of using Oligomer
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The oligomer or polymer is soluble in the monomer
No tackifier or other added oligomer is disclosed or claimed
The oligomer further comprises a lipophilic moiety
Examples of using Antisense
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Antisense RNAs can be classified in different ways
In a separate embodiment new antisense oligodeoxynucleotides are provided
Antisense polynucleotides can include deoxyribonucleotides or ribonucleotides
