Examples of 'antisense oligonucleotides' in a sentence
Meaning of "antisense oligonucleotides"
Antisense oligonucleotides are short strands of DNA or RNA that are designed to bind to complementary sequences of messenger RNA (mRNA), interfering with gene expression. They are often used in biological research and therapeutic applications to modify gene activity or treat genetic disorders
How to use "antisense oligonucleotides" in a sentence
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antisense oligonucleotides
The cellular uptake of antisense oligonucleotides is low.
Antisense oligonucleotides may be single or double stranded.
Oligonucleotides can be either sense or antisense oligonucleotides.
Antisense oligonucleotides for treatment of cancer stem cells.
Complementary oligonucleotides are commonly described as being antisense oligonucleotides.
Chimeric antisense oligonucleotides are one form of oligomeric compound.
It is preferred that the oligonucleotides be antisense oligonucleotides.
The antisense oligonucleotides can be present at any concentration.
Of particular interest are ribozymes and antisense oligonucleotides.
Antisense oligonucleotides may also have sugar mimetics.
Cells are treated with antisense oligonucleotides by routine methods.
Antisense oligonucleotides may be administered as part of a pharmaceutical composition.
Phosphorothioate antisense oligonucleotides may be used.
Antisense oligonucleotides for treatment of cancer.
In a preferred invention the antisense oligonucleotides are synthesized as phosphorothionates.
See also
Antisense oligonucleotides can be used either singly or in combination.
Lipofectin was used to deliver antisense oligonucleotides to the cells.
The antisense oligonucleotides are administered to a patient with obesity.
New applications for antisense oligonucleotides.
Several antisense oligonucleotides may also be used in combination.
Oligonucleotides of the invention may be sense or antisense oligonucleotides.
In certain embodiments antisense oligonucleotides may be shortened or truncated.
Naturally occurring nucleic acids are used as antisense oligonucleotides.
Antisense oligonucleotides were prepared as described above.
We now provide improved compounds incorporating antisense oligonucleotides.
The antisense oligonucleotides are administered to a patient with schizophrenia.
Oligonucleotides disclosed herein may be sense or antisense oligonucleotides.
Morpholino antisense oligonucleotides are amply described in the literature.
Oligonucleotides may be sense or antisense oligonucleotides.
Typically antisense oligonucleotides will be synthesized on automated synthesizers.
Thus antisense molecules can be ribozymes or antisense oligonucleotides.
Delivery of antisense oligonucleotides and siRNA.
Oligonucleotides of the invention are either sense or antisense oligonucleotides.
Antisense oligonucleotides can be synthesized using commercially available synthesizers.
One approach is to use high concentrations of antisense oligonucleotides.
Antisense oligonucleotides can be chemically synthesized according to standard procedures.
It is way to increase the cellular uptake of antisense oligonucleotides.
Antisense oligonucleotides may also be administered by means of this invention.
Chemical modifications and new generations of antisense oligonucleotides.
Antisense oligonucleotides for the treatment of leber congenital amaurosis.
The sequence of the sense and antisense oligonucleotides are as follow.
Antisense oligonucleotides of the gene coding for this protein were prepared.
Such compounds may include antisense oligonucleotides and ribozymes.
Oligonucleotides of the present disclosure are either sense or antisense oligonucleotides.
Antisense oligonucleotides for treating allergy and neoplastic cell proliferation.
Size effect on the in vitro biological activity of antisense oligonucleotides.
Derivatives or modified products of antisense oligonucleotides can be used as antisense oligonucleotides.
Oligonucleotides of the invention can be either sense or antisense oligonucleotides.
Such antisense oligonucleotides may be constructed to inhibit expression of a target gene.
Methods for treating multiple sclerosis using antisense oligonucleotides.
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Antisense RNAs can be classified in different ways
In a separate embodiment new antisense oligodeoxynucleotides are provided
Antisense polynucleotides can include deoxyribonucleotides or ribonucleotides
Examples of using Oligonucleotides
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Longer oligonucleotides lead to increased transformation efficiency
Corresponding synthetic miRNA oligonucleotides were used as standards
Two oligonucleotides are constructed from this sequence
