Examples of 'antisense oligonucleotide' in a sentence
Meaning of "antisense oligonucleotide"
Antisense oligonucleotide: a short single-stranded DNA or RNA molecule that is designed to bind specifically to a target messenger RNA (mRNA) molecule, preventing its translation or causing its degradation
How to use "antisense oligonucleotide" in a sentence
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antisense oligonucleotide
Two kinds of antisense oligonucleotide DNAs were produced.
The compound of the invention is an antisense oligonucleotide.
An antisense oligonucleotide selected from the group of.
A particularly preferred such agent is antisense oligonucleotide.
An antisense oligonucleotide can be chemically modified.
The antisense compound is an antisense oligonucleotide.
The antisense oligonucleotide comprises a morpholino.
The second strand may itself be an antisense oligonucleotide.
Antisense oligonucleotide inhibition experiments can also be undertaken.
A carrier for an antisense oligonucleotide can be used.
The oligonucleotide of the present invention is an antisense oligonucleotide.
An antisense oligonucleotide or equivalent thereof can be delivered as is to a cell.
In alternative embodiments the oligonucleotide may be an antisense oligonucleotide.
An antisense oligonucleotide preparation method.
The oligomer according to the invention is an antisense oligonucleotide.
See also
antisense nucleic acids
antisense oligomer
antisense oligonucleotides
antisense oligonucleotides can
antisense oligomer
antisense oligonucleotides
antisense oligonucleotides can
The antisense oligonucleotide is then produced in vivo through transcription.
The compound according to the invention is an antisense oligonucleotide.
The antisense oligonucleotide was the same used for sequencing.
Yu decided to try a new type of drug called an antisense oligonucleotide.
An antisense oligonucleotide may or may not exhibit absolute complementarity.
In another embodiment the oligonucleotide is not an antisense oligonucleotide or a ribozyme.
An antisense oligonucleotide conjugate comprising.
A particular example of a complementary nucleic acid segment is an antisense oligonucleotide.
Alternatively use an antisense oligonucleotide directed to a direct modifier of a transcriptional regulator.
The formation of colonies can be seen to be inhibited by antisense oligonucleotide.
Antisense oligonucleotide drugs are one of the newer areas of drug development.
One or more internucleotide linkages in the antisense oligonucleotide may be modified.
Antisense oligonucleotide name.
An oligonucleotide as used herein preferably comprises an antisense oligonucleotide or antisense oligoribonucleotide.
Antisense oligonucleotide compositions.
There is no particular upper or lower limit to the antisense oligonucleotide or siRNA.
The antisense oligonucleotide can be used to selectively suppress certain cellular functions.
In order to obtain dsRNA both a sense and an antisense oligonucleotide template are required.
The antisense oligonucleotide may interfere with mRNA of the target organism.
Modifications may be introduced to an antisense oligonucleotide to improve its ability to cross membranes.
The antisense oligonucleotide may also contain a backbone similar to a neutral peptide.
Another preferred embodiment includes an antisense oligonucleotide for treating brain tumors.
Such an antisense oligonucleotide may selectively hybridise with the desired gene.
The second agent is administered concomitantly or sequentially with the antisense oligonucleotide.
Increasingly more antisense oligonucleotide becomes entrapped as the ethanol concentration is increased.
Expression of a metastatic marker gene can be altered using an antisense oligonucleotide sequence.
The antisense oligonucleotide of the invention may also be enclosed within liposomes.
It is preferred that the means to direct the compound comprises an antisense oligonucleotide.
Nusinersen is an antisense oligonucleotide that boosts the expression of a vital motor neuron gene.
A simple example is the inhibition of protein biosynthesis by an antisense oligonucleotide bound to mRNA.
The concentration of antisense oligonucleotide used varies from cell line to cell line.
Several selection criteria are available to contribute to the optimization of antisense oligonucleotide antagonists.
Antisense oligonucleotide tolerability and pharmacokinetic profile in the liver and kidney was evaluated.
Phosphorothioates are very widely used modification in antisense oligonucleotide ongoing clinical trials.
The antisense oligonucleotide may be administered in any convenient vehicle which is physiologically acceptable.
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Examples of using Oligonucleotide
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The oligonucleotide may be derived synthetically or by cloning
Effect of fusion proteins on oligonucleotide annealing temperature
Oligonucleotide decoys for the treatment of pain
Examples of using Antisense
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Antisense RNAs can be classified in different ways
In a separate embodiment new antisense oligodeoxynucleotides are provided
Antisense polynucleotides can include deoxyribonucleotides or ribonucleotides
