Examples of 'cpg dinucleotide' in a sentence
Meaning of "cpg dinucleotide"
cpg dinucleotide: In genetics, a CpG dinucleotide is a DNA sequence where a cytosine nucleotide is followed by a guanine nucleotide in the linear sequence of bases along its 5' → 3' direction
How to use "cpg dinucleotide" in a sentence
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cpg dinucleotide
The CpG dinucleotide therein is a monomer or a multimer.
The oligonucleotides are characterised in that the CpG dinucleotide is unmethylated.
The CpG dinucleotide is preferably a monomer or multimer.
Preferably one oligonucleotide exists for each CpG dinucleotide.
A CpG dinucleotide can be methylated or unmethylated.
In one embodiment the base sequence is free of CpG dinucleotide.
This is due to recognition of certain CpG dinucleotide sequences that are immunostimulatory.
An immunostimulatory oligonucleotide comprising at least one unmethylated CpG dinucleotide.
This is due to recognition of certain CpG dinucleotide sequences which are immunostimulatory.
In one embodiment the oligonucleotide includes at least one unmethylated CpG dinucleotide.
The methylated CpG dinucleotide and they themselves can alter transcription.
The oligonucleotides are characterized in that the CpG dinucleotide is unmethylated.
Cytosine residues in the CpG dinucleotide context were used for downstream methylation analysis.
The markers were determined from genomic regions containing at least one CpG dinucleotide.
Light grey represents a hypomethylated CpG dinucleotide while darker grey indicates a hypermethylated CpG dinucleotide.
See also
The immunostimulatory oligonucleotide may preferably comprise at least one unmethylated CpG dinucleotide.
Both the additional CpG dinucleotide and the polymorphism are shown in FIG.
The polynucleotides of the present disclosure contain at least one unmethylated CpG dinucleotide.
Following deamination, the CpG dinucleotide becomes a TpG dinucleotide.
Differences in cleavage pattern are indicative for the presence or absence of a methylated CpG dinucleotide.
In general, the cytosine within the CpG dinucleotide was changed to a adenine.
A CpG nucleic acid is a nucleic acid which includes at least one unmethylated CpG dinucleotide.
Preferably, for each CpG dinucleotide analyzed two different oligonucleotides are used.
Methylation data are centred and normalised to one standard deviation for every individual CpG dinucleotide.
Preference for Rp chirality at the CpG dinucleotide in octamer PS-Oligos.
The nucleic acids in accordance with the invention include at least one unmethylated CpG dinucleotide.
At least the C of the CpG dinucleotide is typically, but not necessarily, unmethylated.
MSP primers pairs contain at least one primer which hybridises to a bisulphite treated CpG dinucleotide.
CpG-containing oligonucleotides ( in which the CpG dinucleotide is unmethylated ) also induce a predominantly Thi response.
MSP primers pairs contain at least one primer which hybridizes to a bisulfite treated CpG dinucleotide.
The thymidine immediately 5 ' to the first CpG dinucleotide was also important.
The immunostimulatory oligonucleotide, preferably, compries at least one unmethylated CpG dinucleotide.
The motifs consist of an unmethylated CpG dinucleotide flanked by two 5 ' purines and two 3 ' pyrimidines.
In one embodiment the 3 ' palindromic region includes an unmethylated CpG dinucleotide.
CpG-containing oligonucleotides ( in which the CpG dinucleotide is unmethylated ) also induce a predominantly Th1 response.
In another embodiment the 5 ' palindromic region includes an unmethylated CpG dinucleotide.
ODN 2006 has not only CpG dinucleotide motifs but also a high T content.
Therefore, the sequence of said primers comprises at least one CpG dinucleotide.
A surprisingly strong effect is achieved by the p-chirality at the CpG dinucleotide itself.
Aberrant promoter hypermethylation occurs at the 5-position of cytosine within the CpG dinucleotide.
The composition of claim 1, wherein oligonucleotides include at least one unmethylated CpG dinucleotide.
A " CpG oligonucleotide " is a nucleic acid which includes at least one unmethylated CpG dinucleotide.
In one embodiment, the immunostimulatory nucleic acid or oligonucleotide comprises at least one CpG dinucleotide.
DNA from the purified cells was bisulfite-treated analyzed at various CpG dinucleotide motifs.
Also significantly, the immunostimulatory G, U-containing RNA molecules of the invention do not require a CpG dinucleotide.
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