Examples of 'cpg oligonucleotides' in a sentence
Meaning of "cpg oligonucleotides"
cpg oligonucleotides: short, single-stranded DNA molecules that contain unmethylated cytosine-guanine (CpG) dinucleotides, commonly used in immunotherapy and genetic research
How to use "cpg oligonucleotides" in a sentence
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cpg oligonucleotides
Examples of CpG oligonucleotides have the following sequences.
The vaccine composition described herein comprises CpG oligonucleotides.
The CpG oligonucleotides of the present invention are typically deoxynucleotides.
It was previously established that CpG oligonucleotides are excellent vaccine adjuvants.
It has recently been described that there are different classes of CpG oligonucleotides.
Several different classes of CpG oligonucleotides have recently been described.
The products provided in accordance with the invention are CpG oligonucleotides.
The adjuvant effect of CpG oligonucleotides is further discussed in refs.
CpG oligonucleotides can contain a palindromic sequence.
For example, naked CpG oligonucleotides are used.
Other CpG oligonucleotides can be assayed for efficacy using methods described herein.
Suitably, CpG nucleotides are CpG oligonucleotides.
Preferred CpG oligonucleotides are those indicated in the table hereinabove.
In one embodiment, the TLR9 ligands are CpG oligonucleotides.
The amount of CpG oligonucleotides present in the entrapped particles was calculated against the standard.
See also
In some embodiments, the TIR agonists are TLR9 agonists, particularly CpG oligonucleotides ( or CpG . ODN ).
CpG oligonucleotides are optionally condensed prior to cellular uptake.
Thus, scheduled administration of CpG oligonucleotides and immunopotentiating cytokine is contemplated.
CpG oligonucleotides can be free of a palindrome.
P-class immunostimulatory oligonucleotides are CpG oligonucleotides characterized by the presence of palindromes, generally 6-20 nucleotides long.
CpG oligonucleotides can be divided into multiple classes.
In another embodiment, CpG oligonucleotides are used alone or together with an aluminium salt.
CpG oligonucleotides are presented for cellular uptake by dendritic cells.
Alternatively, endogenous CpG oligonucleotides are isolated from mammalian benign or malignant neoplastic tumors.
CpG oligonucleotides may be used alone or in combination with other adjuvants.
Still other adjuvants are CpG oligonucleotides and double stranded RNA molecules, such as poly ( A ) . poly ( U ).
CpG oligonucleotides are isolated from endogenous sources or synthesized in vivo or in vitro.
Alternatively, CpG oligonucleotides can be produced on a large scale in plasmids and degraded into oligonucleotides.
CpG oligonucleotides ( mouse specific sequence ) were synthesized by Biosynthesis.
Preferred CpG oligonucleotides are 8-100 nucleotides in length and have modified back bones.
CpG oligonucleotides may also induce a TH1 response and may also be included.
CpG oligonucleotides also preferentially induce a TH1 response.
CpG oligonucleotides trigger proliferation by activating a protein inside B cells known as TLR9.
The CpG oligonucleotides may have one or two accessible 5 ' ends.
CpG oligonucleotides can be of lengths up to 100 bases, most preferably of lengths of 20 bases.
CpG oligonucleotides ( mouse specific sequence ) were synthesized by BioSynthesis ( Lewisville, TX ).
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