Examples of 'cpg dinucleotides' in a sentence
Meaning of "cpg dinucleotides"
cpg dinucleotides: Refers to a combination of two nucleotides cytosine and guanine, often found together in DNA sequences
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cpg dinucleotides
The CpG dinucleotides may be methylated or unmethylated.
Immunostimulatory oligonucleotides can be free of CpG dinucleotides.
Thymines among the CpG dinucleotides were scored as unmethylated.
Immunostimulatory oligonucleotides may otherwise be free of CpG dinucleotides.
The recovered cytosines among the CpG dinucleotides were scored as methylated.
In other embodiments the immunostimulatory oligonucleotides are free of CpG dinucleotides.
Methylation occurs specifically at CpG dinucleotides which are frequently found within promoter regions.
The construct may not comprise any CpG dinucleotides.
The CpG dinucleotides of the two sets do not lie opposite to each other.
We know that it occurs predominantly at CpG dinucleotides in mammals.
CpG dinucleotides are underlined and dots indicate identity.
Almost exclusively at CpG dinucleotides.
CpG dinucleotides are typically concentrated in the promoter regions and exons of human genes.
Conveniently the oligonucleotide includes a plurality of unmethylated CpG dinucleotides.
The sequence was designed to eliminate all CpG dinucleotides without altering the amino acid sequence.
See also
Some techniques use primers for assessing the methylation status at CpG dinucleotides.
CpG dinucleotides are grouped per gene.
The open circles in this case are the CpG dinucleotides.
Unmethylated CpG dinucleotides are less frequent in eukaryotic DNA than in bacterial DNA.
Said primer oligonucleotides are preferably characterized in that they do not contain any CpG dinucleotides.
Vertebrate DNA is highly methylated and CpG dinucleotides are underrepresented.
Said primer oligonucleotides are preferably characterised in that they do not contain any CpG dinucleotides.
DNA methylation occurs almost exclusively at CpG dinucleotides reviewed in Cedar et al.
The methylation occurs symmetrically on the cytosine residues on both strands of the CpG dinucleotides.
CpG dinucleotides also act to adjuvant DNA vaccines.
In the construct the enhancer and promoter sequence may not comprise any CpG dinucleotides.
CpG dinucleotides are underlined.
Type B stimulatory CpG ODNs contain a full phosphorothioate backbone with one or more CpG dinucleotides.
Positions of primers, probes and CpG dinucleotides ar highlighted.
In another embodiment the 5 ' palindromic region includes two unmethylated CpG dinucleotides.
In a further embodiment, each cytosine in the CpG dinucleotides present in the sequence is methylated.
Such methods enable the high-throughput detection of methylation of a number of CpG dinucleotides.
Moreover, cleavage rates of CpG dinucleotides also differ between cancer and normal samples.
Methylation is predominantly ( but not exclusively ) located in CpG dinucleotides context.
As a result, CpG dinucleotides occur far less frequently than one would expect by chance.
Further, the application of unmethylated CpG dinucleotides has been described.
A vaccine as claimed in any of claims 1 to 4 wherein the oligonucleotide comprises two CpG dinucleotides.
Bacterial DNA contains unmethylated CpG dinucleotides at a frequency of about one per every 16 bases.
Wherein the enhancer and promoter sequence comprises less than 15 CpG dinucleotides.
Cytosines in CpG dinucleotides can be methylated to form 5-methylcytosines.
In some embodiments, the nucleic acid includes three or more unmethylated CpG dinucleotides.
Cytosines in CpG dinucleotides can be methylated to form 5-methylcytosine.
DNA methylation in regards to epigenetic changes occurs at the cytosine-5 in CpG dinucleotides.
Cytosine in the CpG dinucleotides may be methylated to form 5-methylcytosine.
Humans, has been identified, namely, mutations at CpG dinucleotides.
Genomic CpG dinucleotides can be methylated or unmethylated ( alternatively known as up - and down-methylated respectively ).
Another preferred immunostimulant is an immunostimulatory oligonucleotide containing unmethylated CpG dinucleotides ( " CpG " ).
CpG dinucleotides comprise approximately 1 % human genome.
Yet another example of an immunostimulant is an immunostimulatory oligonucleotide containing unmethylated CpG dinucleotides ( " CpG " ).
Dots indicate identity ; CpG dinucleotides are underlined ; ND = not done.
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Many of the remaining CpG islands appear to be
The CpG rich area is marked in grey
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