Examples of 'kappa light chain' in a sentence
Meaning of "kappa light chain"
kappa light chain: A type of protein chain, specifically referring to the lighter component of an antibody molecule
How to use "kappa light chain" in a sentence
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kappa light chain
Human kappa light chain constant region.
All six antibodies contained the kappa light chain.
Kappa light chain restriction was demonstrated.
Isolation of rearranged kappa light chain variable segments.
The kappa light chain was silenced vía a targeted insertion of a neomycin resistant cassette.
Ck is the constant region of the human kappa light chain.
The ten kappa light chain expression vector inserts were then sequenced.
An exemplary binding protein comprises a kappa light chain constant region.
Kappa light chain RNA splicing.
The light chain can be a lambda light chain or a kappa light chain.
The variable domain of a kappa light chain may also be denoted herein as VK.
The second cistron encodes a second pelB leader operatively linked to a kappa light chain.
The entire wild type human immunoglobulin kappa light chain constant region was used.
The second cistron encoded a second pelB leader operatively linked to a kappa light chain.
This vector lacked Fd and kappa light chain sequences.
See also
The invention also provides humanised antibodies wherein the antibody light chain is a kappa light chain.
This vector lacks Fd and kappa light chain sequences.
The transgenic mouse of claim 1, wherein said light chain is a kappa light chain.
The antibody was determined to be kappa light chain and IgG1 heavy chain.
The antibody was isotyped and found to be an IgGY2b with a kappa light chain.
In some such methods, the human kappa light chain locus is the inserted KCo5 transgene.
The constant region of the AFRA light chain is a typical kappa light chain.
Nucleotide alignment of cynomolgus kappa light chain variable regions with human, rabbit and mouse sequences.
The recombinant light chain may be either a lambda or a kappa light chain constant region.
The selected kappa light chain amino acid sequence is reported in Figure 1.
The human light chain constant region preferably is a human kappa light chain constant region.
The sequences of the kappa light chain gene with stuffers is depicted in Table 10.
The Cλ light chain constant region was replaced with a kappa light chain constant region Ck.
TABLE 5 List of kappa light chain interface residues and.
The KM mouse contains a human heavy chain transchromosome and a human kappa light chain transgene.
The table lists the pairs of Kappa light chain and IgG1 heavy chain tested.
In some embodiments, the CDRs are from a kappa light chain.
CDR3 region of the kappa light chain was defined between conserved C codon and FGXG motif.
Preferably, the antibody comprises a kappa light chain constant region.
The binding partners used comprised 15 nucleobases complementary to sequences in the Kappa light chain.
Inactivation of the mouse immunoglobulin kappa light chain J and constant region.
A kappa light chain CDR2 having the sequence,.
Particularly, the antibody comprises a kappa light chain constant region.
Kappa light chain CDR2 regions having the sequence,.
The isotype of the purified antibody was IgG1 with kappa light chain.
Heavy chain, kappa light chain.
Moreover, the antibody may comprise of either a lambda or a kappa light chain.
The mice further comprise human heavy and kappa light chain loci, including 4 Vk gene segments.
L6 mice contain an inserted human heavy chain and an inserted human kappa light chain.
Specifically, an antibody kappa light chain ( VkCk ) library was generated from human B-cells.
The antibody contained an IgG2b heavy chain and a kappa light chain.
Moreover, they carry a human kappa light chain transgene, KCo5, as described in Fishwild et al.
In one embodiment, the light chain constant region is a kappa light chain constant region.
The mouse carries a human kappa light chain transgene, KCo5, as described in Fishwild et al.
Example 9 describes the design of antibody variable heavy chain and kappa light chain leader primers.
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