Examples of 'lambda light chain' in a sentence
Meaning of "lambda light chain"
Lambda light chain: In biology, this phrase refers to a type of polypeptide chain found in antibodies. These chains are important components for the function of antibodies
How to use "lambda light chain" in a sentence
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lambda light chain
Human lambda light chain.
Or isotype and can comprise a kappa or lambda light chain.
Kappa and lambda light chain reactions are set up separately.
Transgenic animals bearing human ig lambda light chain genes.
This target is free lambda light chain expressed on the surface of myeloma cells.
Amplification of IgG heavy chain and lambda light chain genes.
Method of cloning a lambda light chain variable domain using a human lambda light chain mouse.
Two of the variants developed varied in the lambda light chain.
The light chain can be a lambda light chain or a kappa light chain.
Each heavy chain may be prepared with a kappa or lambda light chain.
The Lambda light chain sequences are shown in italic.
Method of making antibodies using a human lambda light chain mouse.
In other systems, the lambda light chain constant region replaces the kappa constant region.
Antibodies comprising a light chain may comprise kappa or lambda light chain.
Table 8 shows a preferred focused lambda light chain diversity in accordance with this invention.
See also
Each heavy chain class may be bound with either a kappa or lambda light chain.
The sequence of the lambda light chain gene with stuffers is depicted in Table 11.
Each heavy chain class can be bound with either a kappa or lambda light chain.
TABLE 4 List of lambda light chain interface residues and.
Each heavy chain class can be paired with either kappa or lambda light chain.
A12 antibodies having kappa or lambda light chain constant regions were tested.
In another embodiment ; the antibody or portion thereof comprises a lambda light chain.
The endogenous mouse immunoglobulin kappa and lambda light chain loci were intact and functional.
In another disclosure, the antibody or portion thereof comprises a lambda light chain.
A lambda light chain CDR2 having the sequence,.
In some embodiments, the CDRs are from a lambda light chain.
Lambda light chain CDR2 regions having the sequence,.
Thus, the mouse does not make a functional endogenous lambda light chain.
A lambda light chain CDR3 selected from the group consisting of,.
Preferably, the light chain constant region is a lambda light chain constant region.
Lambda light chain framework 1 specific primers are those used in Example 4.
In one embodiment, the mouse may comprise a non-functional lambda light chain locus.
LC-ESI-Q-TOF MS experiments were also performed on a commercially available lambda light chain.
The antibody is not binding to an IgG1 that comprises a lambda light chain constant domain.
Primary diagnosis, cardiovascular amyloidosis AL type deposition of lambda light chain.
XENOMOUSE ™ mice may further contain approximately all of the human lambda light chain locus.
In other embodiments, XENOMOUSE ™ mice further contain approximately all of the lambda light chain locus.
The antibody of 10 further comprising a kappa or lambda light chain.
The isotype of all antibodies to said 16OHE1-glucuronide fraction is IgG1 with lambda light chain.
IgM, IgE, IgD, etc . or isotype and can comprise a kappa or lambda light chain.
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