Examples of 'light chain constant' in a sentence
Meaning of "light chain constant"
light chain constant: A term used in biochemistry to refer to a part of an antibody molecule. It is the constant region of the light chain that remains unchanged and is responsible for certain functions of the antibody
How to use "light chain constant" in a sentence
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light chain constant
Human kappa light chain constant region.
Light chain constant regions can be lambda or kappa.
Nonlimiting exemplary light chain constant regions include λ and k.
Light chain constant domain regions appear in amber.
Various aspects encompass light chain constant region sequences.
The light chain constant region is human kappa.
Various embodiments encompass light chain constant region sequences.
A light chain constant region.
An immunoglobulin constant domain refers to a heavy or light chain constant domain.
Preferably the light chain constant region is cKappa.
An exemplary binding protein comprises a kappa light chain constant region.
Light chain constant regions are shown with a checkerboard pattern.
The mouse may further comprise a human light chain constant sequence.
The light chain constant region may be an immunoglobulin k constant region.
The recombinant light chain may be either a lambda or a kappa light chain constant region.
See also
The light chain constant region is represented with a checkerboard pattern.
The entire wild type human immunoglobulin kappa light chain constant region was used.
The light chain constant region can be chosen from kappa or lambda.
Each light chain comprises a light chain variable domain VL and a light chain constant domain CL.
The light chain constant region consists of either kappa or lambda chains.
Co-expression of the light chain constant region.
Light chain constant region amino assay sequence is available on public databases.
In another embodiment the human light chain constant region is a kappa chain or a lambda chain.
In some embodiments, a light chain comprises at least a portion of a light chain constant region.
The light chain constant domain may be a kappa or lambda constant domain.
Comprises a human light chain constant region ;.
The light chain constant region can be of the kappa or lambda type.
Preferably, the antibody comprises a kappa light chain constant region.
The light chain constant domain may be of either the kappa or lambda type.
Particularly, the antibody comprises a kappa light chain constant region.
The human light chain constant region preferably is a human kappa light chain constant region.
In one instance, the antibody comprises a kappa light chain constant region.
The light chain constant region includes a CL domain.
In a particular embodiment of the invention, the light chain constant region is a kappa chain.
The light chain constant region consists of a CL domain.
In another specific aspect, the mouse further comprises a human light chain constant sequence.
The immunoglobulin light chain constant region is a Ck region.
In another specific embodiment, the mouse further comprises a human light chain constant sequence.
The λ light chain constant gene is an intact mouse Cλ gene.
The antibody is not binding to an IgG1 that comprises a lambda light chain constant domain.
A human immunoglobulin light chain constant region was derived vía amplification of cDNA by a PCR reaction.
In any of the embodiments described herein, the antibodies may comprise a k light chain constant region.
The Cλ light chain constant region was replaced with a kappa light chain constant region Ck.
In one aspect, the second immunoglobulin light chain constant region is from a non-human animal.
The light chain constant region includes k and A isotype.
In another embodiment the heavy and light chain constant regions are derived from murine IgG1.
In addition, the immunoglobulin constant region of the present invention includes a light chain constant region.
Preferably, the light chain constant region is the kappa type.
More preferably, the antibody additionally contains one or two light chain constant and / or variable domains.
In various cases, the light chain constant region is an immunoglobulin k constant region.
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