Examples of 'heavy chain constant' in a sentence
Meaning of "heavy chain constant"
Heavy chain constant: A metaphorical expression indicating a burdensome or oppressive force or factor that remains consistent or unchanging
How to use "heavy chain constant" in a sentence
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heavy chain constant
The immunoglobulin mu heavy chain constant region was used.
Heavy chain constant domain regions appear in red.
Each antibody has a different heavy chain constant domain.
The heavy chain constant region comprises three domains.
An immunoglobulin moiety may comprise a heavy chain constant region.
Preferably the heavy chain constant region is derived from an antibody locus.
The main immunogenicity is mediated by the heavy chain constant regions.
Preferably the heavy chain constant region is derived from an immunoglobulin locus.
The linker also included a standard heavy chain constant region.
The heavy chain constant region may further comprise a hinge region.
An immunoglobulin moiety that comprises a heavy chain constant region of an immunoglobulin.
The heavy chain constant domain is preferably an IgG class constant domain.
These are dictated by the structure of the heavy chain constant region.
Nonlimiting exemplary heavy chain constant regions also include e and µ.
All immunoglobulins within a given class have very similar heavy chain constant regions.
See also
The heavy chain constant region is primarily responsible for effector function.
Fc fragments are generated entirely from the heavy chain constant region of an immunoglobulin.
And a heavy chain constant region deriving from human IgG and a human constant light chain region.
It is possible to fuse the entire heavy chain constant region to the lectin sequence.
The immunoglobulin constant region of the present invention includes a heavy chain constant region.
The number of heavy chain constant region domains will depend on the isotype.
Within another related embodiment the second portion is an immunoglobulin heavy chain constant region.
The sequences of human heavy chain constant region genes are known in the art.
The immunoglobulin constant domain sequence can be an immunoglobulin heavy chain constant domain sequence.
In one embodiment the human heavy chain constant region is a human IgG constant region.
The immunoglobulin gene that lacks the sequence is one or more heavy chain constant genes.
It is possible to fuse the entire heavy chain constant region to the adhesin sequence.
The heavy chain constant regions that correspond to IgGI is called Yi chain.
The mouse would further comprise a mouse heavy chain constant region modification as described herein.
The heavy chain constant regions of the IgG class are identified with the Greek symbol Y.
Comprises a human heavy chain constant region ;.
Heavy chain constant regions are composed of several domains, eg.
The immunoglobulin heavy chain constant region is an Fc region.
An " isotype " is a class of antibodies defined by the heavy chain constant region.
A preferred human heavy chain constant region is IgG3.
In one embodiment, the second portion is an immunoglobulin heavy chain constant region.
Human heavy chain constant region derived from IgG4.
A domain, of an immunoglobulin heavy chain constant region.
And the heavy chain constant region is selected from the group consisting of,.
An immunoglobulin light or heavy chain constant domain, and.
Typically, the heavy chain constant region is human or a modified form of a human constant region.
In some embodiments, the immunoglobulin constant region is a heavy chain constant region.
In some aspects, the heavy chain constant region of an antibody is afucosylated.
In some embodiments, the immunoglobulin constant domain is a heavy chain constant domain.
As is known, each immunoglobulin heavy chain constant region includes four or five domains.
Preferably, a humanized or chimeric antibody comprises an IgG heavy chain constant region.
As is known, each immunoglobulin heavy chain constant region comprises four or five domains.
A fusión of a first integrin subunit and an immunoglobulin heavy chain constant domain, and.
In further embodiments, the heavy chain constant region or fragment thereof is a human IgG1.
In some embodiments, a heavy chain comprises at least a portion of a heavy chain constant region.
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