Examples of 'light chain constant region' in a sentence
Meaning of "light chain constant region"
Light chain constant region: In the context of immunology and protein structure, this refers to a specific part of an antibody molecule. Antibodies are made up of two heavy chains and two light chains, with the constant region of the light chain being a crucial component for antigen binding and immune response
How to use "light chain constant region" in a sentence
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light chain constant region
Human kappa light chain constant region.
An exemplary binding protein comprises a kappa light chain constant region.
Preferably the light chain constant region is cKappa.
The recombinant light chain may be either a lambda or a kappa light chain constant region.
The light chain constant region is human kappa.
Various aspects encompass light chain constant region sequences.
A light chain constant region.
Various embodiments encompass light chain constant region sequences.
The light chain constant region may be an immunoglobulin k constant region.
The entire wild type human immunoglobulin kappa light chain constant region was used.
The light chain constant region is represented with a checkerboard pattern.
Co-expression of the light chain constant region.
The light chain constant region can be chosen from kappa or lambda.
Preferably, the antibody comprises a kappa light chain constant region.
The light chain constant region consists of either kappa or lambda chains.
See also
Particularly, the antibody comprises a kappa light chain constant region.
Light chain constant region amino assay sequence is available on public databases.
In another embodiment the human light chain constant region is a kappa chain or a lambda chain.
In some embodiments, a light chain comprises at least a portion of a light chain constant region.
The light chain constant region can be of the kappa or lambda type.
In one instance, the antibody comprises a kappa light chain constant region.
The human light chain constant region preferably is a human kappa light chain constant region.
In a particular embodiment of the invention, the light chain constant region is a kappa chain.
The light chain constant region includes a CL domain.
In one aspect, the second immunoglobulin light chain constant region is from a non-human animal.
The light chain constant region consists of a CL domain.
In any of the embodiments described herein, the antibodies may comprise a k light chain constant region.
The immunoglobulin light chain constant region is a Ck region.
In addition, the immunoglobulin constant region of the present invention includes a light chain constant region.
A human immunoglobulin light chain constant region was derived vÃa amplification of cDNA by a PCR reaction.
Optionally, the VI is linked to a light chain constant region.
The Cλ light chain constant region was replaced with a kappa light chain constant region Ck.
In one embodiment, the immunoglobulin light chain constant region is a Ck region.
The light chain constant region includes k and A isotype.
In one aspect, the immunoglobulin light chain constant region is a Ck region.
The light chain constant region is comprised of one domain, CL.
The animal of embodiment 1, wherein the immunoglobulin light chain constant region is a Ck region.
Preferably, the light chain constant region is the kappa type.
A screening probe was synthesised, complementary to mouse immunoglobulin light chain constant region by PCR amplification.
In various cases, the light chain constant region is an immunoglobulin k constant region.
This plasmid contained a CMV promoter, and a sequence encoding the human light chain constant region.
By way of example, the light chain constant region can be kappa or lambda.
The pConKappa0.4 vector contains the kappa light chain constant region.
In various embodiments, the light chain constant region is an immunoglobulin k constant region.
A light chain may comprise a light chain variable region ( VL ) and a light chain constant region ( CL ).
Preferably, the light chain constant region is a lambda light chain constant region.
SEQ ID NO, 11 is the amino acid sequence of an exemplary light chain constant region.
In preferred embodiments, the light chain constant region can be a kappa or lambda constant region.
The construct encoded SEQ ID NO, 19 fused to a human Kappa light chain constant region.
In one embodiment, the light chain constant region is a kappa light chain constant region.
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