Examples of 'light chain variable domain' in a sentence
Meaning of "light chain variable domain"
Light chain variable domain: In immunology, the variable domain of an antibody's light chain, which plays a crucial role in binding to antigens
How to use "light chain variable domain" in a sentence
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light chain variable domain
E light chain variable domain nucleotide sequence.
The multivalent antibody herein four light chain variable domain polypeptides.
The light chain variable domain is aligned with the variable domain of the heavy chain.
This is done independently for both the heavy and light chain variable domain sequences.
A light chain variable domain comprising,.
This region consists of a dimer of one heavy chain and one light chain variable domain.
Method of cloning a lambda light chain variable domain using a human lambda light chain mouse.
In other embodiments, the immunoglobulin single variable domain is a light chain variable domain.
Each light chain comprises a light chain variable domain VL and a light chain constant domain CL.
A respective amino acid sequence that essentially consists of a light chain variable domain sequence e . g.
A light chain variable domain of the amino acid sequence,.
In one embodiment VI represents a light chain variable domain.
The light chain variable domain sequence of the protein comprises the following CDRs,.
In one embodiment Vx represents a light chain variable domain.
A light chain variable domain having the sequence, and / or a heavy chain variable domain having the sequence,.
See also
In one embodiment Vxx represents a light chain variable domain.
An anti-VEGF antibody light chain variable domain comprising the amino acid sequence,.
In some methods, the second nucleic acid encodes a Lambda-type light chain variable domain.
The polypeptide sequence of the light chain variable domain of mAQC2 is shown below,.
In one aspect, the human anti-MUC18 antibody has a heavy and light chain variable domain.
In particular embodiments, the light chain variable domain is a human light chain variable domain.
In one embodiment, the antibody single variable domain is a light chain variable domain ( VI ).
A translation of the light chain variable domain is presented in Figure 4.
In another embodiment, the immunoglobulin variable domain polypeptide comprises a light chain variable domain ( VI ).
In one embodiment residue 71 of the light chain variable domain is replaced with tyrosine.
Each fragment contains a heavy chain variable domain ( VH ) concatenated to a light chain variable domain ( VL ).
A first domain VLA being a light chain variable domain specific for a first antigen A ;.
Figure 6 depicts the amino acid sequence of the 2F8 light chain variable domain.
The antibody comprises four light chain variable domain polypeptides, which each, optionally, comprise a CL domain.
A ligand, antibody or fragment thereof according to Claim 7, having a light chain variable domain which comprises.
Optionally, the light chain variable domain comprises the amino acid sequence of SEQ ID NO, 9.
The antibody disclosed herein may comprise a light chain variable domain of SEQ ID NO, 6.
Mature light chain variable domain protein sequence B 12.
The method of claim 43 wherein each light chain variable domain is identical.
The light chain variable domain may be encoded by human VkO12/Jk3 genes.
In one embodiment residue 38 of the light chain variable domain is replaced with lysine.
The FRP5 light chain variable domain coding region is isolated as a SacI / BamHI fragment from pMZ18/1.
In some embodiments, the human immunoglobulin light chain variable domain is a k light chain variable domain.
Figure 9 depicts the nucleotide sequence of the A12 light chain variable domain.
Rat 23E12 light chain variable domain DNA with signal sequence.
In some examples, an anti-CD22 antibody comprises a light chain variable domain as depicted in below.
The antibody may comprise a light chain variable domain of SEQ ID NO, 6.
The multispecific antibody of any of claims 17-21, wherein each light chain variable domain is identical.
A first domain VIA being a light chain variable domain specific for CD3 ;.
The first stage involved the gene synthesis of a " humanised " light chain variable domain gene ( HuVLLYS° ).
The antibody comprises a light chain variable domain of SEQ ID NO, 18.
Figure 2 shows comparisons of mouse anti-human IL-23p19 antibody clone light chain variable domain sequences.
A fourth domain comprising a binding region of a light chain variable domain of the second immunoglobulin ( VL2 ).
In one embodiment, the antibody comprises a light chain variable domain of SEQ ID NO, 6.
Figure 2 shows the complete sequence of the light chain variable domain of mouse monoclonal antibody 5/44 ;.
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