Examples of 'nucleotide analogue' in a sentence
Meaning of "nucleotide analogue"
nucleotide analogue: A nucleotide analogue is a compound that is structurally similar to a nucleotide, which is a basic structural unit of DNA and RNA. These analogues are often used in research or medical settings to study nucleic acid function or as antiviral or anticancer agents
How to use "nucleotide analogue" in a sentence
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nucleotide analogue
Nucleotide analogue polymerase inhibitor.
Nucleoside analogues and oligonucleotide derivative comprising nucleotide analogue thereof.
It is a nucleotide analogue.
The RNA molecule according to the invention contains at least one modified nucleotide analogue.
Tenofovir is an adenosine nucleotide analogue currently commercially available with activity against retroviruses.
Adefovir and its salts and its derivatives - a nucleotide analogue.
A further preferred nucleotide analogue of the invention is wherein the internucleoside phosphate linkage is a phosphorothioate.
In one embodiment the antisense strand comprises at least 1 nucleotide analogue.
A preferred nucleotide analogue of the invention is INA.
This viral enzyme converts acyclovir into acyclovir monophosphate, a nucleotide analogue.
The nucleotide analogue is preferably not a PNA building block.
In one aspect, the anti-viral is a nucleotide analogue reverse transcriptase inhibitor.
A nucleotide analogue is a nucleotide containing a modification at for instance the base, sugar, or phosphate moieties.
An oligonucleotide according to claim 3, wherein the nucleotide analogue comprises a modified base.
At least one nucleotide analogue can be incorporated into the DNA.
See also
An antisense oligonucleotide according to claim 5, wherein the nucleotide analogue has a modified base.
In a preferred embodiment, a nucleotide analogue or equivalent comprises a modified backbone.
An oligonucleotide equivalent according to claim 4, wherein the nucleotide analogue has a modified base.
BrdU ( bromodeoxyuridine ) is a nucleotide analogue of thymidine used for labeling of proliferating cells.
An antisense oligonucleotide according to claim 5, wherein the nucleotide analogue has a modified backbone.
In one embodiment the nucleotide analogue is a pyrene 2 ' - amino-LNA monomer or a adamantly 2-amino-LNA monomer.
In another embodiment, the siRNA molecule may contain at least one modified nucleotide analogue.
In one emdodiement the nucleotide analogue is " ENA ".
This viral enzyme converts Aciclovir into Aciclovir monophosphate, a nucleotide analogue.
In one embodiment the nucleotide analogue is " ENA ".
In one embodiment, the first, second and / or further RNA molecules may comprise a nucleotide analogue.
In this regard, Cidovir ( CDV ) as a nucleotide analogue is already phosphorylated and thus active.
In some embodiments, said non-LNA unit is another nucleotide analogue unit.
Gemcitabine ( Gemzar ® ) ( HCl ) is a nucleotide analogue antimetabolite that exhibits antitumour activity.
In some embodiments, the non-LNA unit " x " is another nucleotide analogue unit.
Tenofovir alafenamide, A pro-drug of the nucleotide analogue Tenofovir, critical for HIV treatment.
A method of item 55, wherein the high-affinity nucleotide analogue is INA.
An oligonucleotide according to claim 5, wherein the nucleotide analogue is a LNA ( locked nucleic acid ).
Usage, Acyclic phosphonate nucleotide analogue.
Table 5 . Mitochondrial toxicities of nucleoside and nucleotide analogue HIV-1 RT-inhibitors.
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Analogue signals should be filtered to remove noise
Examples of using Nucleotide
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Sofosbuvir is a nucleotide prodrug that is extensively metabolised
Each pair is made up of something called a nucleotide
All of your nucleotide sequences are accounted for
