Examples of 'proteasome inhibitor' in a sentence
Meaning of "proteasome inhibitor"
proteasome inhibitor - a type of medication that blocks the action of proteasomes, which are important in the growth and division of cells
How to use "proteasome inhibitor" in a sentence
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proteasome inhibitor
Said proteasome inhibitor may be as described above.
Velcade is a targeted therapy classified as a proteasome inhibitor.
It is a type of proteasome inhibitor and dipeptidyl boronic acid.
The additional therapeutic agent is a proteasome inhibitor.
The proteasome inhibitor is as described above.
This injection medication is classified as proteasome inhibitor.
The proteasome inhibitor may be bortezomib.
Velcade is an agent known as a proteasome inhibitor.
Examples of the proteasome inhibitor may include bortezomib.
Assays of the invention may be conducted in the presence of a proteasome inhibitor.
Bortezomib is a proteasome inhibitor.
The proteasome inhibitor may be administered in a single dose or in repeat doses.
Velcade is a proteasome inhibitor.
Proteasome inhibitor also is intended to include pharmaceutically acceptable salts of the compounds.
Participants who could not tolerate a proteasome inhibitor or immunomodulatory drugs are allowed.
See also
Biomarkers for assessing peripheral neuropathy response to treatment with a proteasome inhibitor.
The amount of proteasome inhibitor that can be solubilized is dependent on several parameters.
In some of the foregoing embodiments the additional therapeutic agent is a proteasome inhibitor.
Administration of the proteasome inhibitor may be by any suitable method as described above.
Also described herein is the method of preparing a pharmaceutical composition of a proteasome inhibitor.
Examples of the proteasome inhibitor may include bortezomib and the like.
The invention provides sensitive methods for monitoring proteasome inhibitor drug action.
Penn study finds proteasome inhibitor leads to higher than expected rates of cardiovascular adverse events.
A further aspect of this invention involves the method of preparing a pharmaceutical composition of a proteasome inhibitor.
The present disclosure also relates to the use of a proteasome inhibitor for attenuating physiological ageing.
Proteasome Inhibitor is being developed using TRAP technology for the treatment of cancer.
Mechanism of action Bortezomib is a proteasome inhibitor.
VELCADE is a proteasome inhibitor used to treat multiple myeloma.
In some embodiments, the chemotherapeutic agent is a proteasome inhibitor.
VELCADE is a proteasome inhibitor used to treat mutiple myeloma.
B t = activation factor determined upon titration of the proteasome inhibitor.
HIV proteasome inhibitor is being developed for the treatment of HIV Proteasome inhibitor infections.
In the invention, the proteasome inhibitor is bortezomib.
In certain preferred embodiments, the NF-kB activation inhibitor is a proteasome inhibitor.
Ixazomib, a proteasome inhibitor that is given by mouth.
A non-limiting example of a peptide boronate proteasome inhibitor is bortezomib.
The first non-peptidic proteasome inhibitor discovered was the natural product lactacystin.
In some embodiments, the therapeutic agent is preferably a proteasome inhibitor.
In some embodiments, the proteasome inhibitor is carfilzomib.
However, a pH should be selected to provide suitable stability of the proteasome inhibitor.
In certain embodiments, the proteasome inhibitor is administered subcutaneously.
As expected, this effect was reversed in the presence of proteasome inhibitor treatment.
In some embodiments, the proteasome inhibitor is a peptidyl boronic acid.
In certain embodiments, the cancer treatment comprises administering a proteasome inhibitor to a patient.
The proteasome inhibitor can be administered in treatment cycles, with a rest between cycles.
In certain preferred embodiments, the proteasome inhibitor may be administered intratumorally.
Table 1 identifies markers whose expression correlates with responsiveness to a proteasome inhibitor.
The use according to claim 11 wherein said proteasome inhibitor is a lactacystin analog.
Suitably, the pharmaceutical composition is administered before during or after administration of a proteasome inhibitor.
Preferably, the proteasome inhibitor is a dry powder prior to its addition to the cyclodextrin solution.
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Examples of using Proteasome
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Similar proteasome inhibition by carfilzomib was achieved with
The biological consequences of proteasome inhibition are numerous
The proteasome participates in the degradation ofcyclins
